Telomeres and telomerase

N. M V Gomes, J. W. Shay, W. E. Wright

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

Abstract

Telomere-based replicative senescence is thought to function as a potent mechanism of tumor protection in humans. Whether this mechanism is conserved in other species is still unclear. In this review we present an inter-species critical overview of some of the available literature on the fundamental biology of telomeres and telomerase during development, regeneration, cancer and aging of living organisms during their evolutionary journey through time.

Original languageEnglish (US)
Title of host publicationThe Comparative Biology of Aging
PublisherSpringer Netherlands
Pages227-258
Number of pages32
ISBN (Print)9789048134649
DOIs
StatePublished - 2010

Fingerprint

telomerase
Telomerase
telomeres
Telomere
neoplasms
Cell Aging
Regeneration
Neoplasms
Biological Sciences
organisms

Keywords

  • Amphibians
  • Birds
  • Evolution
  • Fish
  • Invertebrates
  • Mammals
  • Telomerase
  • Telomeres
  • Vertebrates

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Gomes, N. M. V., Shay, J. W., & Wright, W. E. (2010). Telomeres and telomerase. In The Comparative Biology of Aging (pp. 227-258). Springer Netherlands. https://doi.org/10.1007/978-90-481-3465-6-11

Telomeres and telomerase. / Gomes, N. M V; Shay, J. W.; Wright, W. E.

The Comparative Biology of Aging. Springer Netherlands, 2010. p. 227-258.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gomes, NMV, Shay, JW & Wright, WE 2010, Telomeres and telomerase. in The Comparative Biology of Aging. Springer Netherlands, pp. 227-258. https://doi.org/10.1007/978-90-481-3465-6-11
Gomes NMV, Shay JW, Wright WE. Telomeres and telomerase. In The Comparative Biology of Aging. Springer Netherlands. 2010. p. 227-258 https://doi.org/10.1007/978-90-481-3465-6-11
Gomes, N. M V ; Shay, J. W. ; Wright, W. E. / Telomeres and telomerase. The Comparative Biology of Aging. Springer Netherlands, 2010. pp. 227-258
@inbook{14ee11f4910042808c8683ab814fcc72,
title = "Telomeres and telomerase",
abstract = "Telomere-based replicative senescence is thought to function as a potent mechanism of tumor protection in humans. Whether this mechanism is conserved in other species is still unclear. In this review we present an inter-species critical overview of some of the available literature on the fundamental biology of telomeres and telomerase during development, regeneration, cancer and aging of living organisms during their evolutionary journey through time.",
keywords = "Amphibians, Birds, Evolution, Fish, Invertebrates, Mammals, Telomerase, Telomeres, Vertebrates",
author = "Gomes, {N. M V} and Shay, {J. W.} and Wright, {W. E.}",
year = "2010",
doi = "10.1007/978-90-481-3465-6-11",
language = "English (US)",
isbn = "9789048134649",
pages = "227--258",
booktitle = "The Comparative Biology of Aging",
publisher = "Springer Netherlands",

}

TY - CHAP

T1 - Telomeres and telomerase

AU - Gomes, N. M V

AU - Shay, J. W.

AU - Wright, W. E.

PY - 2010

Y1 - 2010

N2 - Telomere-based replicative senescence is thought to function as a potent mechanism of tumor protection in humans. Whether this mechanism is conserved in other species is still unclear. In this review we present an inter-species critical overview of some of the available literature on the fundamental biology of telomeres and telomerase during development, regeneration, cancer and aging of living organisms during their evolutionary journey through time.

AB - Telomere-based replicative senescence is thought to function as a potent mechanism of tumor protection in humans. Whether this mechanism is conserved in other species is still unclear. In this review we present an inter-species critical overview of some of the available literature on the fundamental biology of telomeres and telomerase during development, regeneration, cancer and aging of living organisms during their evolutionary journey through time.

KW - Amphibians

KW - Birds

KW - Evolution

KW - Fish

KW - Invertebrates

KW - Mammals

KW - Telomerase

KW - Telomeres

KW - Vertebrates

UR - http://www.scopus.com/inward/record.url?scp=77957605548&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957605548&partnerID=8YFLogxK

U2 - 10.1007/978-90-481-3465-6-11

DO - 10.1007/978-90-481-3465-6-11

M3 - Chapter

SN - 9789048134649

SP - 227

EP - 258

BT - The Comparative Biology of Aging

PB - Springer Netherlands

ER -