Telomeres are double-strand DNA breaks hidden from DNA damage responses

Jerry W. Shay, Woodring E. Wright

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

A network of ATM/ATR-mediated events regulates cell cycle checkpoints and genomic integrity and contributes to the processing of DNA double-strand breaks in both genomic DNA and at telomeres. In yeast and in human cells, investigators, including Takata et al. (2004), and Herbig et al., published in this issue of Molecular Cell, are beginning to decipher the signaling pathways involved at the telomeres.

Original languageEnglish (US)
Pages (from-to)420-421
Number of pages2
JournalMolecular cell
Volume14
Issue number4
DOIs
StatePublished - May 21 2004

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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