Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

Katherine Noelani Chang, Shan Zhong, Matthew T. Weirauch, Gary Hon, Mattia Pelizzola, Hai Li, Shao Shan Carol Huang, Robert J. Schmitz, Mark A. Urich, Dwight Kuo, Joseph R. Nery, Hong Qiao, Ally Yang, Abdullah Jamali, Huaming Chen, Trey Ideker, Bing Ren, Ziv Bar-Joseph, Timothy R. Hughes, Joseph R. Ecker

Research output: Contribution to journalArticle

162 Citations (Scopus)

Abstract

The gaseous plant hormone ethylene regulates a multitude of growth and developmental processes. How the numerous growth control pathways are coordinated by the ethylene transcriptional response remains elusive. We characterized the dynamic ethylene transcriptional response by identifying targets of the master regulator of the ethylene signaling pathway, ETHYLENE INSENSITIVE3 (EIN3), using chromatin immunoprecipitation sequencing and transcript sequencing during a timecourse of ethylene treatment. Ethylene-induced transcription occurs in temporal waves regulated by EIN3, suggesting distinct layers of transcriptional control. EIN3 binding was found to modulate a multitude of downstream transcriptional cascades, including a major feedback regulatory circuitry of the ethylene signaling pathway, as well as integrating numerous connections between most of the hormone mediated growth response pathways. These findings provide direct evidence linking each of the major plant growth and development networks in novel ways. Copyright Chang et al.

Original languageEnglish (US)
Article numbere00675
JournaleLife
Volume2013
Issue number2
DOIs
StatePublished - Jun 11 2013

Fingerprint

Arabidopsis
Growth Hormone
Gases
ethylene
Plant Growth Regulators
Plant Development
Chromatin Immunoprecipitation
Transcription
Growth
Growth and Development
Chromatin
Hormones
Feedback

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Chang, K. N., Zhong, S., Weirauch, M. T., Hon, G., Pelizzola, M., Li, H., ... Ecker, J. R. (2013). Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. eLife, 2013(2), [e00675]. https://doi.org/10.7554/eLife.00675

Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. / Chang, Katherine Noelani; Zhong, Shan; Weirauch, Matthew T.; Hon, Gary; Pelizzola, Mattia; Li, Hai; Carol Huang, Shao Shan; Schmitz, Robert J.; Urich, Mark A.; Kuo, Dwight; Nery, Joseph R.; Qiao, Hong; Yang, Ally; Jamali, Abdullah; Chen, Huaming; Ideker, Trey; Ren, Bing; Bar-Joseph, Ziv; Hughes, Timothy R.; Ecker, Joseph R.

In: eLife, Vol. 2013, No. 2, e00675, 11.06.2013.

Research output: Contribution to journalArticle

Chang, KN, Zhong, S, Weirauch, MT, Hon, G, Pelizzola, M, Li, H, Carol Huang, SS, Schmitz, RJ, Urich, MA, Kuo, D, Nery, JR, Qiao, H, Yang, A, Jamali, A, Chen, H, Ideker, T, Ren, B, Bar-Joseph, Z, Hughes, TR & Ecker, JR 2013, 'Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis', eLife, vol. 2013, no. 2, e00675. https://doi.org/10.7554/eLife.00675
Chang, Katherine Noelani ; Zhong, Shan ; Weirauch, Matthew T. ; Hon, Gary ; Pelizzola, Mattia ; Li, Hai ; Carol Huang, Shao Shan ; Schmitz, Robert J. ; Urich, Mark A. ; Kuo, Dwight ; Nery, Joseph R. ; Qiao, Hong ; Yang, Ally ; Jamali, Abdullah ; Chen, Huaming ; Ideker, Trey ; Ren, Bing ; Bar-Joseph, Ziv ; Hughes, Timothy R. ; Ecker, Joseph R. / Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. In: eLife. 2013 ; Vol. 2013, No. 2.
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