Tetanus immunity in elderly people

Susan M. Murphy, Deirdre M. Hegarty, Conleth S. Feighery, J. Bernard Walsh, Yvonne Williams, Davis P. Coakley

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The aims of this study were to document the level of tetanus immunity in elderly people; to assess the value of immunization history in predicting tetanus immune status and to determine the response to tetanus immunization in elderly people compared with younger subjects. One-hundred day-hospital attenders (group 1), 100 long-term-care residents (group 2) and 50 young subjects (group 3) were recruited. Protective titres of tetanus antitoxin antibodies were detected in 20% of group 1, 45% of group 2 and 80% of group 3. Tetanus immunization history was a poor predictor of immune status in older people with a positive predictive value of 50% and a negative predictive value of 76%. The response to tetanus immunization was slower and of lower magnitude in older people. However, 36 of 37 older subjects developed protective levels of tetanus antitoxin antibodies on completion of a primary immunization programme.

Original languageEnglish (US)
Pages (from-to)99-102
Number of pages4
JournalAge and Ageing
Volume24
Issue number2
DOIs
StatePublished - Mar 1995

Fingerprint

Tetanus
Immunity
Immunization
Tetanus Antitoxin
History
Immunization Programs
Antibodies
Long-Term Care

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Aging

Cite this

Murphy, S. M., Hegarty, D. M., Feighery, C. S., Walsh, J. B., Williams, Y., & Coakley, D. P. (1995). Tetanus immunity in elderly people. Age and Ageing, 24(2), 99-102. https://doi.org/10.1093/ageing/24.2.99

Tetanus immunity in elderly people. / Murphy, Susan M.; Hegarty, Deirdre M.; Feighery, Conleth S.; Walsh, J. Bernard; Williams, Yvonne; Coakley, Davis P.

In: Age and Ageing, Vol. 24, No. 2, 03.1995, p. 99-102.

Research output: Contribution to journalArticle

Murphy, SM, Hegarty, DM, Feighery, CS, Walsh, JB, Williams, Y & Coakley, DP 1995, 'Tetanus immunity in elderly people', Age and Ageing, vol. 24, no. 2, pp. 99-102. https://doi.org/10.1093/ageing/24.2.99
Murphy SM, Hegarty DM, Feighery CS, Walsh JB, Williams Y, Coakley DP. Tetanus immunity in elderly people. Age and Ageing. 1995 Mar;24(2):99-102. https://doi.org/10.1093/ageing/24.2.99
Murphy, Susan M. ; Hegarty, Deirdre M. ; Feighery, Conleth S. ; Walsh, J. Bernard ; Williams, Yvonne ; Coakley, Davis P. / Tetanus immunity in elderly people. In: Age and Ageing. 1995 ; Vol. 24, No. 2. pp. 99-102.
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