TFIIS and GreB: Two like-minded transcription elongation factors with sticky fingers

Ronald C. Conaway, Stephanie E. Kong, Joan Weliky Conaway

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

How the structurally distinct transcription factor TFIIS from eukaryotes and its bacterial counterpart GreB act to convert their cognate RNA polymerases into ribonucleases has been a longstanding question. Now, two new structures of these factors bound to their respective RNA polymerases (Opalka et al. and Kettenberger et al. [this issue of Cell]) suggest how they accomplish this feat.

Original languageEnglish (US)
Pages (from-to)272-274
Number of pages3
JournalCell
Volume114
Issue number3
DOIs
StatePublished - Aug 8 2003
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

Fingerprint

Dive into the research topics of 'TFIIS and GreB: Two like-minded transcription elongation factors with sticky fingers'. Together they form a unique fingerprint.

Cite this