The 16-item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): A psychometric evaluation in patients with chronic major depression

A. John Rush, Madhukar H. Trivedi, Hicham M. Ibrahim, Thomas J. Carmody, Bruce Arnow, Daniel N. Klein, John C. Markowitz, Philip T. Ninan, Susan Kornstein, Rachel Manber, Michael E. Thase, James H. Kocsis, Martin B. Keller

Research output: Contribution to journalArticle

1893 Scopus citations

Abstract

Background: The 16-item Quick Inventory of Depressive Symptomatology (QIDS), a new measure of depressive symptom severity derived from the 30-item Inventory of Depressive Symptomatology (IDS), is available in both self-report (QIDS-SR16) and clinician-rated (QIDS-C16) formats. Methods: This report evaluates and compares the psychometric properties of the QIDS-SR16 in relation to the IDS-SR30 and the 24-item Hamilton Rating Scale for Depression (HAM-D24) in 596 adult outpatients treated for chronic nonpsychotic, major depressive disorder. Results: Internal consistency was high for the QIDS-SR16 (Cronbach's α = .86), the IDS-SR30 (Cronbach's α = .92), and the HAM-D24 (Cronbach's α = .88). QIDS-SR16 total scores were highly correlated with IDS-SR30 (.96) and HAM-D 24 (.86) total scores. Item-total correlations revealed that several similar items were highly correlated with both QIDS-SR16 and IDS-SR30 total scores. Roughly 1.3 times the QIDS-SR16 total score is predictive of the HAM-D17 (17-item version of the HAM-D) total score. Conclusions: The QIDS-SR16 was as sensitive to symptom change as the IDS-SR30 and HAM-D24, indicating high concurrent validity for all three scales. The QIDS-SR16 has highly acceptable psychometric properties, which supports the usefulness of this brief rating of depressive symptom severity in both clinical and research settings.

Original languageEnglish (US)
Pages (from-to)573-583
Number of pages11
JournalBiological Psychiatry
Volume54
Issue number5
DOIs
StatePublished - Sep 1 2003

Keywords

  • Chronic major depression
  • Concurrent validity
  • Psychometric properties
  • Quick Inventory of Depressive Symptomatology
  • Self-reports
  • Symptom severity

ASJC Scopus subject areas

  • Biological Psychiatry

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