The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field

Donald M. Small, Libo Wang, Matthew A. Mitsche

Research output: Contribution to journalReview article

28 Citations (Scopus)

Abstract

This review focuses on some new techniques to study the behavior of peptides and proteins bound to oil droplets. We will show how model peptides e.g., amphipathic a helices (AaH) and amphipathic b strand (AβS) and some apolipoproteins adsorb to triacylglycerol (TAG) droplets and how they behave once adsorbed to the interface. While most of the studies described involve peptides and proteins at an oil/water interface, studies can also be carried out when the surface has been partially covered with phospholipids. This work is important because it examines biophysical changes that take place at lipid droplet interfaces and how this may relate to the metabolism of lipoproteins and lipid droplets.

Original languageEnglish (US)
JournalJournal of Lipid Research
Volume50
Issue numberSUPPL.
DOIs
StatePublished - Apr 1 2009

Fingerprint

Adsorption
Oils
Peptides
Water
Proteins
Apolipoproteins
Lipids
Lipoproteins
Phospholipids
Triglycerides
Metabolism
Lipid Droplets

Keywords

  • Adiposomes
  • Apolipoproteins
  • Fat bodies
  • Fat metabolism
  • Lipid droplets
  • Obesity
  • Oil droplets
  • Surface pressure
  • Surface tension

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Endocrinology

Cite this

The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field. / Small, Donald M.; Wang, Libo; Mitsche, Matthew A.

In: Journal of Lipid Research, Vol. 50, No. SUPPL., 01.04.2009.

Research output: Contribution to journalReview article

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