The association between gender and outcome of patients with upper tract urothelial cancer

Yii Her Chou, Wei Chiao Chang, Wen Jeng Wu, Ching Chia Li, Hsin Chih Yeh, Ming Feng Hou, Ping Song Chou, Mei Hui Lee, Wei Pin Chang, Wei Ming Li

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The incidence of upper tract urothelial cancer (UTUC) has gradually increased over the past 30 years. Although most reports have shown that UTUC occurs more frequently in men than in women, women have been found to have a worse prognosis than men. In Taiwan, a high incidence of UTUC has been reported, with an unusual minor predominance of female cases. The purpose of this study was to determine the influence of gender on the outcome of patients with UTUC after nephroureterectomy and bladder cuff excision. From January 1990 to December 2007, 301 patients diagnosed with UTUC were admitted at our institution. A retrospective analysis of the effect of gender on the clinical outcome was performed. We compared the 5-year bladder recurrence-free, progression-free, and disease-specific survival rates. While we did not observe any differences between men and women in bladder recurrence-free, progression-free, or disease-specific survival rates, we found that female patients had a significantly higher percentage of contralateral recurrence than the males (5.9% vs. 0.8%, p = 0.019).

Original languageEnglish (US)
Pages (from-to)37-42
Number of pages6
JournalKaohsiung Journal of Medical Sciences
Volume29
Issue number1
DOIs
StatePublished - Jan 2013

Keywords

  • Gender
  • Nephroureterectomy
  • Outcome
  • Upper tract urothelial cancer
  • Urothelial cancer

ASJC Scopus subject areas

  • Medicine(all)

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