The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus

Edgar J G Peters, David G. Armstrong, Robert P. Wunderlich, Jan Bosma, Susan Stacpoole-Shea, Lawrence A. Lavery

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the effect of galvanic electrical stimulation on vascular perfusion in diabetic patients. Nineteen subjects with diabetes were enrolled. Eleven subjects (57.9%) were diagnosed with impaired peripheral perfusion based upon their initial transcutaneous oximetry values (<40 mm Hg). The subjects were studied over a 2-day period. On the 1st day, one foot was electrically stimulated for four 60-minute periods by an external electrical stimulation device. Vascular perfusion of both feet was assessed before and after the sessions of electrical stimulation. On the 2nd day, no electrical stimulation was applied and noninvasive vascular measurements were repeated. For the 1st hour, transcutaneous oxygen pressure was measured continuously during stimulation at the lateral aspect of the leg. Subsequently, perfusion between the periods of stimulation was measured on the dorsum of the foot with both transcutaneous oximetry and laser Doppler flowmetry after each stimulation period. In the group with impaired peripheral perfusion, a significant rise in tissue oxygenation as compared to the control measurements was measured during the first 5 minutes of stimulation (p < .040). For those without vascular disease (T(c)pO2 > 40 mm Hg) however, there was not a significant increase compared to baseline (p = .280). After the periods of stimulation, the stimulated feet did not show any higher perfusion levels than the control feet. Patterns in perfusion during the day, as measured by laser Doppler flowmetry, were similar in the tested feet and in the controls. These data suggest that external subsensory electrical stimulation induces a transient rise in skin perfusion in persons with diabetes and impaired peripheral perfusion.

Original languageEnglish (US)
Pages (from-to)396-400
Number of pages5
JournalJournal of Foot and Ankle Surgery
Volume37
Issue number5
StatePublished - Sep 1998

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Electric Stimulation
Diabetes Mellitus
Perfusion
Foot
Transcutaneous Blood Gas Monitoring
Laser-Doppler Flowmetry
Blood Vessels
Skin

Keywords

  • Diabetes
  • Electricity
  • Perfusion
  • Ulceration

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Peters, E. J. G., Armstrong, D. G., Wunderlich, R. P., Bosma, J., Stacpoole-Shea, S., & Lavery, L. A. (1998). The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus. Journal of Foot and Ankle Surgery, 37(5), 396-400.

The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus. / Peters, Edgar J G; Armstrong, David G.; Wunderlich, Robert P.; Bosma, Jan; Stacpoole-Shea, Susan; Lavery, Lawrence A.

In: Journal of Foot and Ankle Surgery, Vol. 37, No. 5, 09.1998, p. 396-400.

Research output: Contribution to journalArticle

Peters, EJG, Armstrong, DG, Wunderlich, RP, Bosma, J, Stacpoole-Shea, S & Lavery, LA 1998, 'The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus', Journal of Foot and Ankle Surgery, vol. 37, no. 5, pp. 396-400.
Peters EJG, Armstrong DG, Wunderlich RP, Bosma J, Stacpoole-Shea S, Lavery LA. The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus. Journal of Foot and Ankle Surgery. 1998 Sep;37(5):396-400.
Peters, Edgar J G ; Armstrong, David G. ; Wunderlich, Robert P. ; Bosma, Jan ; Stacpoole-Shea, Susan ; Lavery, Lawrence A. / The benefit of electrical stimulation to enhance perfusion in persons with diabetes mellitus. In: Journal of Foot and Ankle Surgery. 1998 ; Vol. 37, No. 5. pp. 396-400.
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