TY - JOUR
T1 - The Burden of Movement Disorders in Cameroon
T2 - A Rural and Urban-Based Inpatient/Outpatient Study
AU - Cubo, Esther
AU - Doumbe, Jacques
AU - Mapoure Njankouo, Yacouba
AU - Nyinyikua, Theophile
AU - Kuate, Callixte
AU - Ouyang, Bichun
AU - Shah, Hiral
AU - Calvo, Sara
AU - Fernandez-Sierra, Abel
AU - Kompoliti, Katie
AU - Njiengwe, Erero
AU - Louis, Elan D.
N1 - Funding Information:
funded by the World Federation of Neurology and the International Parkinson’s Disease and Movement Disorder Society. The authors report no other sources of funding and no conflicts of interest. Financial Disclosures for the previous 12 months: Esther Cubo reports travel and speech grants from AbbVie, Allergan, and UCB. Katie Kompoliti reports consulting fees from Neurocrine, US World Meds, and Cynapsus. Elan D. Louis MD, has received research support from the National Institutes of Health, National Institute of Neurological Disorders and Stroke (NINDS) R01 NS042859 (principal investigator), NINDS R01 NS39422 (principal investigator), NINDS R01 NS086736 (principal investigator), NINDS R01 NS073872 (principal investigator), NINDS R01 NS085136 (principal investigator), and NINDS R01 NS088257 (principal investigator). The remaining authors report no sources of funding and no conflicts of interest.
Publisher Copyright:
© 2017 International Parkinson and Movement Disorder Society
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Background: Because of rapid demographic changes, the prevalence of movement disorders (MDs) is expected to increase in Africa. The objective of this study was to estimate the prevalence of MDs in an inpatient/outpatient-based study of rural and urban health care centers in Cameroon. Methods: In this retrospective medical chart review, the inpatient/outpatients settings covered an urban population (3,000,000) and a rural population (380,276). Neurological diseases were classified according to the International Statistical Classification of Diseases-Related Health Problems, 10th revision (ICD-10). Crude prevalence was calculated per 100 with 95% confidence intervals (CIs). Results: Of 20,131 medical charts reviewed (13% from the rural area), 4187 patients (20.8%) with neurological complaints were identified. MDs were diagnosed exclusively from urban centers in 134 patients (3.2%): the mean patient age was 48.6 ± 18.6 years, and 54.7% were women. The most prevalent MDs were hyperkinetic movements (tremor, myoclonus, and drug-induced MDs [ICD-10 code G25]; prevalence, 1.19%; 95% CI, 1.192–1.194%), Parkinson's disease (ICD-10 code G20; prevalence, 0.78%; 95% CI, 0.785–0.787%), dystonia (ICD-10 code G24; prevalence, 0.61%; 95% CI, 0.612–0.613%), secondary parkinsonism (ICD-10 code G21; prevalence, 0.56%; 95% CI, 0.564–0.565%), Huntington's disease (ICD-10 code G10; prevalence, 0.09%; 95% CI, 0.091–0.092%), and ataxia (ICD-10 code R29; prevalence, 0.04%; 95% CI, 0.0451–0.0456). Conclusion: Although the burden of MDs is expected to increase, MDs are likely underdiagnosed in rural areas. High-quality movement disorder training is essential to tackle this need.
AB - Background: Because of rapid demographic changes, the prevalence of movement disorders (MDs) is expected to increase in Africa. The objective of this study was to estimate the prevalence of MDs in an inpatient/outpatient-based study of rural and urban health care centers in Cameroon. Methods: In this retrospective medical chart review, the inpatient/outpatients settings covered an urban population (3,000,000) and a rural population (380,276). Neurological diseases were classified according to the International Statistical Classification of Diseases-Related Health Problems, 10th revision (ICD-10). Crude prevalence was calculated per 100 with 95% confidence intervals (CIs). Results: Of 20,131 medical charts reviewed (13% from the rural area), 4187 patients (20.8%) with neurological complaints were identified. MDs were diagnosed exclusively from urban centers in 134 patients (3.2%): the mean patient age was 48.6 ± 18.6 years, and 54.7% were women. The most prevalent MDs were hyperkinetic movements (tremor, myoclonus, and drug-induced MDs [ICD-10 code G25]; prevalence, 1.19%; 95% CI, 1.192–1.194%), Parkinson's disease (ICD-10 code G20; prevalence, 0.78%; 95% CI, 0.785–0.787%), dystonia (ICD-10 code G24; prevalence, 0.61%; 95% CI, 0.612–0.613%), secondary parkinsonism (ICD-10 code G21; prevalence, 0.56%; 95% CI, 0.564–0.565%), Huntington's disease (ICD-10 code G10; prevalence, 0.09%; 95% CI, 0.091–0.092%), and ataxia (ICD-10 code R29; prevalence, 0.04%; 95% CI, 0.0451–0.0456). Conclusion: Although the burden of MDs is expected to increase, MDs are likely underdiagnosed in rural areas. High-quality movement disorder training is essential to tackle this need.
KW - Huntington's disease
KW - Parkinson's disease
KW - ataxia
KW - dystonia
KW - epidemiology
KW - essential tremor
KW - myoclonus
KW - prevalence
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U2 - 10.1002/mdc3.12474
DO - 10.1002/mdc3.12474
M3 - Article
C2 - 30363499
AN - SCOPUS:85067377820
SN - 2330-1619
VL - 4
SP - 568
EP - 573
JO - Movement Disorders Clinical Practice
JF - Movement Disorders Clinical Practice
IS - 4
ER -