The Causative Agent of Bacillary Angiomatosis

R. J. Birtles; T. G. Harrison; A. G. Taylor; D. A. Relman; T. M. Schmidt; C. J. Cockerell; P. M. Tierno; A. E. Friedman-Kien; K. S. Kim

doi:10.1056/NEJM199111143252014

The Causative Agent of Bacillary Angiomatosis

R. J. Birtles, T. G. Harrison, A. G. Taylor, D. A. Relman, T. M. Schmidt, C. J. Cockerell, P. M. Tierno, A. E. Friedman-Kien, K. S. Kim

Research output: Contribution to journal › Letter › peer-review

18 Scopus citations

Abstract

To the Editor: We report that the bacillary angiomatosis agent, BA-TF, described by Relman and colleagues,¹ is very closely related to but distinct from Bartonella bacilliformis. Our evidence is based on an analysis of the 16S ribosomal RNA (rRNA) gene sequence. We used the polymerase chain reaction (PCR) to amplify the 16S rRNA gene of B. bacilliformis (strain NCTC12138) and then used linear PCR sequencing of the product² to obtain over 90 percent (1401 bases) of the 16S rRNA gene sequence. This was aligned with other available eubacterial sequence data,³ and regions of ambiguity were removed to ensure that.

Original language	English (US)
Pages (from-to)	1447-1448
Number of pages	2
Journal	New England Journal of Medicine
Volume	325
Issue number	20
DOIs	https://doi.org/10.1056/NEJM199111143252014
State	Published - Nov 14 1991

ASJC Scopus subject areas

General Medicine

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10.1056/NEJM199111143252014

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title = "The Causative Agent of Bacillary Angiomatosis",

abstract = "To the Editor: We report that the bacillary angiomatosis agent, BA-TF, described by Relman and colleagues,1 is very closely related to but distinct from Bartonella bacilliformis. Our evidence is based on an analysis of the 16S ribosomal RNA (rRNA) gene sequence. We used the polymerase chain reaction (PCR) to amplify the 16S rRNA gene of B. bacilliformis (strain NCTC12138) and then used linear PCR sequencing of the product2 to obtain over 90 percent (1401 bases) of the 16S rRNA gene sequence. This was aligned with other available eubacterial sequence data,3 and regions of ambiguity were removed to ensure that.",

author = "Birtles, {R. J.} and Harrison, {T. G.} and Taylor, {A. G.} and Relman, {D. A.} and Schmidt, {T. M.} and Cockerell, {C. J.} and Tierno, {P. M.} and Friedman-Kien, {A. E.} and Kim, {K. S.}",

year = "1991",

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doi = "10.1056/NEJM199111143252014",

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T1 - The Causative Agent of Bacillary Angiomatosis

AU - Birtles, R. J.

AU - Harrison, T. G.

AU - Taylor, A. G.

AU - Relman, D. A.

AU - Schmidt, T. M.

AU - Cockerell, C. J.

AU - Tierno, P. M.

AU - Friedman-Kien, A. E.

AU - Kim, K. S.

PY - 1991/11/14

Y1 - 1991/11/14

N2 - To the Editor: We report that the bacillary angiomatosis agent, BA-TF, described by Relman and colleagues,1 is very closely related to but distinct from Bartonella bacilliformis. Our evidence is based on an analysis of the 16S ribosomal RNA (rRNA) gene sequence. We used the polymerase chain reaction (PCR) to amplify the 16S rRNA gene of B. bacilliformis (strain NCTC12138) and then used linear PCR sequencing of the product2 to obtain over 90 percent (1401 bases) of the 16S rRNA gene sequence. This was aligned with other available eubacterial sequence data,3 and regions of ambiguity were removed to ensure that.

AB - To the Editor: We report that the bacillary angiomatosis agent, BA-TF, described by Relman and colleagues,1 is very closely related to but distinct from Bartonella bacilliformis. Our evidence is based on an analysis of the 16S ribosomal RNA (rRNA) gene sequence. We used the polymerase chain reaction (PCR) to amplify the 16S rRNA gene of B. bacilliformis (strain NCTC12138) and then used linear PCR sequencing of the product2 to obtain over 90 percent (1401 bases) of the 16S rRNA gene sequence. This was aligned with other available eubacterial sequence data,3 and regions of ambiguity were removed to ensure that.

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The Causative Agent of Bacillary Angiomatosis

Abstract

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