The development and scope of a versatile tandem Stille-oxa-electrocyclization reaction

Uttam K. Tambar, Taichi Kano, John F. Zepernick, Brian M. Stoltz

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

A palladium-catalyzed tandem Stille-oxa-electrocyclization reaction has been developed for the convergent preparation of highly substituted polycyclic pyran systems. The strategy presented in this letter is an alternative to the known methods for constructing similar pyran systems. The substrate scope of this diastereoselective transformation is explored.

Original languageEnglish (US)
Pages (from-to)345-350
Number of pages6
JournalTetrahedron Letters
Volume48
Issue number3
DOIs
StatePublished - Jan 15 2007

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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