The diuretic phase of respiratory distress syndrome and its relationship to oxygenation

Craig B. Langman, William D. Engle, Stephen Baumgart, William W. Fox, Richard A. Polin

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

To determine the relationship between improvement in pulmonary function and diuresis in respiratory distress syndrome, ten consecutive premature infants requiring mechanical ventilation for severe RDS were studied. Every infant had a diuresis (output/intake >80%), which began at 26 to 34 hours of life and which lasted for an additional 64-72 hours. The diuresis preceded significant improvement in AaDo2 and ventilator settings (IMV, PIP, PEEP) by 52 hours. There was a significant decrease in body weight among all study infants during the first four days of life despite an increase in fluid intake. This study suggests a relationship in RDS between improvement in oxygenation and removal of interstitial lung edema.

Original languageEnglish (US)
Pages (from-to)462-466
Number of pages5
JournalThe Journal of pediatrics
Volume98
Issue number3
DOIs
StatePublished - Mar 1981

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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