The early morning rise in blood pressure is related mainly to ambulation

A. F. Khoury, P. Sunderajan, Norman M Kaplan

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

The marked increase in cardiovascular events that occur in the early mornings hours could be related to a significant rise in blood pressure at this time but there is uncertainty as to whether this rise in pressure occurs before, at, or after awakening. Automatic blood pressure and pulse measurements were taken twice on 15 normotensive subjects and three times on 11 untreated hypertensive subjects starting before the onset of sleep and at 10 min intervals for 1 h before and 60 to 90 min after awakening. In random order, all subjects either remained supine or immediately arose and ambulated on the first two occasions. The hypertensives had a third study involving ingestion of 10 mg nifedipine after awakening and remaining supine for the next 60 min. The blood pressure and pulse changed little before and after awakening if the subjects remained supine. They rose rapidly and significantly immediately upon arising. The rise in pressure upon arising was blunted by the prior ingestion of nifedipine. The early morning rise in blood pressure and pulse is mainly related to arising from bed. Possible ways to reduce the abrupt rise in blood pressure and the increase in cardiovascular events that occur after arising are suggested.

Original languageEnglish (US)
Pages (from-to)339-344
Number of pages6
JournalAmerican Journal of Hypertension
Volume5
Issue number6 I
StatePublished - 1992

Fingerprint

Walking
Blood Pressure
Nifedipine
Eating
Pressure
Uncertainty
Sleep

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The early morning rise in blood pressure is related mainly to ambulation. / Khoury, A. F.; Sunderajan, P.; Kaplan, Norman M.

In: American Journal of Hypertension, Vol. 5, No. 6 I, 1992, p. 339-344.

Research output: Contribution to journalArticle

@article{fd4ca1c0b37f4128ac67a5b11fcf22c4,
title = "The early morning rise in blood pressure is related mainly to ambulation",
abstract = "The marked increase in cardiovascular events that occur in the early mornings hours could be related to a significant rise in blood pressure at this time but there is uncertainty as to whether this rise in pressure occurs before, at, or after awakening. Automatic blood pressure and pulse measurements were taken twice on 15 normotensive subjects and three times on 11 untreated hypertensive subjects starting before the onset of sleep and at 10 min intervals for 1 h before and 60 to 90 min after awakening. In random order, all subjects either remained supine or immediately arose and ambulated on the first two occasions. The hypertensives had a third study involving ingestion of 10 mg nifedipine after awakening and remaining supine for the next 60 min. The blood pressure and pulse changed little before and after awakening if the subjects remained supine. They rose rapidly and significantly immediately upon arising. The rise in pressure upon arising was blunted by the prior ingestion of nifedipine. The early morning rise in blood pressure and pulse is mainly related to arising from bed. Possible ways to reduce the abrupt rise in blood pressure and the increase in cardiovascular events that occur after arising are suggested.",
author = "Khoury, {A. F.} and P. Sunderajan and Kaplan, {Norman M}",
year = "1992",
language = "English (US)",
volume = "5",
pages = "339--344",
journal = "Journal of clinical hypertension",
issn = "0895-7061",
publisher = "Oxford University Press",
number = "6 I",

}

TY - JOUR

T1 - The early morning rise in blood pressure is related mainly to ambulation

AU - Khoury, A. F.

AU - Sunderajan, P.

AU - Kaplan, Norman M

PY - 1992

Y1 - 1992

N2 - The marked increase in cardiovascular events that occur in the early mornings hours could be related to a significant rise in blood pressure at this time but there is uncertainty as to whether this rise in pressure occurs before, at, or after awakening. Automatic blood pressure and pulse measurements were taken twice on 15 normotensive subjects and three times on 11 untreated hypertensive subjects starting before the onset of sleep and at 10 min intervals for 1 h before and 60 to 90 min after awakening. In random order, all subjects either remained supine or immediately arose and ambulated on the first two occasions. The hypertensives had a third study involving ingestion of 10 mg nifedipine after awakening and remaining supine for the next 60 min. The blood pressure and pulse changed little before and after awakening if the subjects remained supine. They rose rapidly and significantly immediately upon arising. The rise in pressure upon arising was blunted by the prior ingestion of nifedipine. The early morning rise in blood pressure and pulse is mainly related to arising from bed. Possible ways to reduce the abrupt rise in blood pressure and the increase in cardiovascular events that occur after arising are suggested.

AB - The marked increase in cardiovascular events that occur in the early mornings hours could be related to a significant rise in blood pressure at this time but there is uncertainty as to whether this rise in pressure occurs before, at, or after awakening. Automatic blood pressure and pulse measurements were taken twice on 15 normotensive subjects and three times on 11 untreated hypertensive subjects starting before the onset of sleep and at 10 min intervals for 1 h before and 60 to 90 min after awakening. In random order, all subjects either remained supine or immediately arose and ambulated on the first two occasions. The hypertensives had a third study involving ingestion of 10 mg nifedipine after awakening and remaining supine for the next 60 min. The blood pressure and pulse changed little before and after awakening if the subjects remained supine. They rose rapidly and significantly immediately upon arising. The rise in pressure upon arising was blunted by the prior ingestion of nifedipine. The early morning rise in blood pressure and pulse is mainly related to arising from bed. Possible ways to reduce the abrupt rise in blood pressure and the increase in cardiovascular events that occur after arising are suggested.

UR - http://www.scopus.com/inward/record.url?scp=0026645358&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026645358&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 339

EP - 344

JO - Journal of clinical hypertension

JF - Journal of clinical hypertension

SN - 0895-7061

IS - 6 I

ER -