The effects of ultrasonic energy on peripheral nerves

Implications for ultrasound-assisted liposuction

Brian K. Howard, Samuel J. Beran, Jeffrey M. Kenkel, Joellen Krueger, Rod J. Rohrich

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The integration of ultrasound-assisted liposuction with traditional suction-assisted lipoplasty has extended the role of liposuction in body contouring. Although there are ample data regarding the effects of ultrasound on peripheral nerves from studies with the Cavitron ultrasound surgical aspirator, there is little information concerning the effects of modern ultrasound body contouring equipment on neural tissue. This study was designed to evaluate the functional and histologic effects of ultrasound energy on rat peripheral nerves (sciatic nerves) using a commonly-used ultrasound-assisted liposuction generator. After the application of ultrasound to exposed rat sciatic nerves, operative magnification was used to assess any visible injury. The sciatic function index was serially measured to quantify immediate and long-term functional effects on the nerves. Our results showed immediate visible injury using low amplitude settings (level 6), but no functional evidence of injury until much higher settings were used (level 9). All animals in the groups with initial functional impairment had returned to normal or near-normal function at completion of the study (51 days). Histologic examination revealed no evidence of damage in the low amplitude groups. Histologic analysis of the high amplitude groups displayed diffuse infiltration of the nerve, with foamy histiocytes and an increased number of mast cells, consistent with remote neural injury followed by myelin breakdown and repair.

Original languageEnglish (US)
Pages (from-to)984-989
Number of pages6
JournalPlastic and Reconstructive Surgery
Volume103
Issue number3
StatePublished - 1999

Fingerprint

Lipectomy
Peripheral Nerves
Ultrasonics
Wounds and Injuries
Sciatic Nerve
Histiocytes
Suction
Myelin Sheath
Mast Cells
Equipment and Supplies

ASJC Scopus subject areas

  • Surgery

Cite this

The effects of ultrasonic energy on peripheral nerves : Implications for ultrasound-assisted liposuction. / Howard, Brian K.; Beran, Samuel J.; Kenkel, Jeffrey M.; Krueger, Joellen; Rohrich, Rod J.

In: Plastic and Reconstructive Surgery, Vol. 103, No. 3, 1999, p. 984-989.

Research output: Contribution to journalArticle

Howard, Brian K. ; Beran, Samuel J. ; Kenkel, Jeffrey M. ; Krueger, Joellen ; Rohrich, Rod J. / The effects of ultrasonic energy on peripheral nerves : Implications for ultrasound-assisted liposuction. In: Plastic and Reconstructive Surgery. 1999 ; Vol. 103, No. 3. pp. 984-989.
@article{2b4d161f6b644937bd423e57364be124,
title = "The effects of ultrasonic energy on peripheral nerves: Implications for ultrasound-assisted liposuction",
abstract = "The integration of ultrasound-assisted liposuction with traditional suction-assisted lipoplasty has extended the role of liposuction in body contouring. Although there are ample data regarding the effects of ultrasound on peripheral nerves from studies with the Cavitron ultrasound surgical aspirator, there is little information concerning the effects of modern ultrasound body contouring equipment on neural tissue. This study was designed to evaluate the functional and histologic effects of ultrasound energy on rat peripheral nerves (sciatic nerves) using a commonly-used ultrasound-assisted liposuction generator. After the application of ultrasound to exposed rat sciatic nerves, operative magnification was used to assess any visible injury. The sciatic function index was serially measured to quantify immediate and long-term functional effects on the nerves. Our results showed immediate visible injury using low amplitude settings (level 6), but no functional evidence of injury until much higher settings were used (level 9). All animals in the groups with initial functional impairment had returned to normal or near-normal function at completion of the study (51 days). Histologic examination revealed no evidence of damage in the low amplitude groups. Histologic analysis of the high amplitude groups displayed diffuse infiltration of the nerve, with foamy histiocytes and an increased number of mast cells, consistent with remote neural injury followed by myelin breakdown and repair.",
author = "Howard, {Brian K.} and Beran, {Samuel J.} and Kenkel, {Jeffrey M.} and Joellen Krueger and Rohrich, {Rod J.}",
year = "1999",
language = "English (US)",
volume = "103",
pages = "984--989",
journal = "Plastic and Reconstructive Surgery",
issn = "0032-1052",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - The effects of ultrasonic energy on peripheral nerves

T2 - Implications for ultrasound-assisted liposuction

AU - Howard, Brian K.

AU - Beran, Samuel J.

AU - Kenkel, Jeffrey M.

AU - Krueger, Joellen

AU - Rohrich, Rod J.

PY - 1999

Y1 - 1999

N2 - The integration of ultrasound-assisted liposuction with traditional suction-assisted lipoplasty has extended the role of liposuction in body contouring. Although there are ample data regarding the effects of ultrasound on peripheral nerves from studies with the Cavitron ultrasound surgical aspirator, there is little information concerning the effects of modern ultrasound body contouring equipment on neural tissue. This study was designed to evaluate the functional and histologic effects of ultrasound energy on rat peripheral nerves (sciatic nerves) using a commonly-used ultrasound-assisted liposuction generator. After the application of ultrasound to exposed rat sciatic nerves, operative magnification was used to assess any visible injury. The sciatic function index was serially measured to quantify immediate and long-term functional effects on the nerves. Our results showed immediate visible injury using low amplitude settings (level 6), but no functional evidence of injury until much higher settings were used (level 9). All animals in the groups with initial functional impairment had returned to normal or near-normal function at completion of the study (51 days). Histologic examination revealed no evidence of damage in the low amplitude groups. Histologic analysis of the high amplitude groups displayed diffuse infiltration of the nerve, with foamy histiocytes and an increased number of mast cells, consistent with remote neural injury followed by myelin breakdown and repair.

AB - The integration of ultrasound-assisted liposuction with traditional suction-assisted lipoplasty has extended the role of liposuction in body contouring. Although there are ample data regarding the effects of ultrasound on peripheral nerves from studies with the Cavitron ultrasound surgical aspirator, there is little information concerning the effects of modern ultrasound body contouring equipment on neural tissue. This study was designed to evaluate the functional and histologic effects of ultrasound energy on rat peripheral nerves (sciatic nerves) using a commonly-used ultrasound-assisted liposuction generator. After the application of ultrasound to exposed rat sciatic nerves, operative magnification was used to assess any visible injury. The sciatic function index was serially measured to quantify immediate and long-term functional effects on the nerves. Our results showed immediate visible injury using low amplitude settings (level 6), but no functional evidence of injury until much higher settings were used (level 9). All animals in the groups with initial functional impairment had returned to normal or near-normal function at completion of the study (51 days). Histologic examination revealed no evidence of damage in the low amplitude groups. Histologic analysis of the high amplitude groups displayed diffuse infiltration of the nerve, with foamy histiocytes and an increased number of mast cells, consistent with remote neural injury followed by myelin breakdown and repair.

UR - http://www.scopus.com/inward/record.url?scp=0033015270&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033015270&partnerID=8YFLogxK

M3 - Article

VL - 103

SP - 984

EP - 989

JO - Plastic and Reconstructive Surgery

JF - Plastic and Reconstructive Surgery

SN - 0032-1052

IS - 3

ER -