Abstract
PURPOSE: To evaluate the efficacy of combined particulate embolization and single stage stereotactic radiosurgery in the treatment of large arteriovenous malformations (AVMs) of the brain. METHODS: Twenty-four patients with barge brain AVMs (diameter >3.0 cm; volume > 14 cm3), who had previously undergone particulate embolization and stereotactic radiosurgery, were retrospectively evaluated 2 or more years after radiosurgery. RESULTS: In 12 (50%) of these patients there was complete AVM obliteration, comparing favorably with a 58% obliteration rate in a group of AVMs having a 4- to 10- cm3 volume, treated by radiosurgery alone. Recanalization of embolized, but not radiated, AVM segments was identified in 3 (12%) patients. However, long- term occlusion was demonstrated in the embolized portions of most AVMs subsequently treated by radiosurgery. Complications included 1 (4%) patient with a mild upper extremity paresis after radiosurgery and 2 (8%) patients with transient neurologic deficits after embolization. CONCLUSION: Combined embolization and stereotactic radiosurgery was more efficacious than radiosurgery alone for large brain AVMs. Recanalization after embolization did occur but was a relatively minor cause of treatment failure.
Original language | English (US) |
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Pages (from-to) | 299-306 |
Number of pages | 8 |
Journal | American Journal of Neuroradiology |
Volume | 16 |
Issue number | 2 |
State | Published - Jan 1 1995 |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology