The efficacy of sustained-release thioridazine in the treatment of schizophrenic inpatients

J. Herrera, J. Costa, J. Sramek, C. Heh, D. Khaled, M. Gutierrez, J. Ananth

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A sustained-release form of thioridazine was recently developed as an aid to improving outpatient compliance with medication regimens and decreasing inpatient costs associated with medication distribution and administration. Fifteen patients with acute schizophrenia were entered into a placebo-controlled double-blind evaluation of thioridazine sustained-release, which was given once daily for four weeks. Tests of efficacy at endpoint revealed a significant mediation effect (P < 0.05), which was already evident by the end of week 1 (P < 0.05).

Original languageEnglish (US)
Pages (from-to)1006-1011
Number of pages6
JournalCurrent Therapeutic Research - Clinical and Experimental
Volume48
Issue number6
StatePublished - 1990
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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