The endocrinology of extrapyramidal system disorders

B. Kirkpatrick, C. A. Tamminga

Research output: Contribution to journalArticle

Abstract

The study of endocrinologic changes in Parkinson's disease, Huntington's disease, and tardive dyskinesia may elucidate the pathophysiology of these disorders, especially the presence of hypothalamic lesions. There is probably a decrease in PRL concentrations in Parkinson's disease, and there may be an increase in TSH response to TRH stimulation. It is not clear if there is any change in GH concentrations in Parkinson's disease. There appears to be a robust increase in GH concentrations in Huntington's disease, and there may be a small increase in PRL as well. At present no endocrinologic abnormality has been well documented in tardive dyskinesia.

Original languageEnglish (US)
Pages (from-to)159-172
Number of pages14
JournalNeurologic Clinics
Volume6
Issue number1
StatePublished - 1988

Fingerprint

Basal Ganglia Diseases
Endocrinology
Parkinson Disease
Huntington Disease
Tardive Dyskinesia

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

The endocrinology of extrapyramidal system disorders. / Kirkpatrick, B.; Tamminga, C. A.

In: Neurologic Clinics, Vol. 6, No. 1, 1988, p. 159-172.

Research output: Contribution to journalArticle

Kirkpatrick, B. ; Tamminga, C. A. / The endocrinology of extrapyramidal system disorders. In: Neurologic Clinics. 1988 ; Vol. 6, No. 1. pp. 159-172.
@article{97226fc245de439ba9f9751967cf0318,
title = "The endocrinology of extrapyramidal system disorders",
abstract = "The study of endocrinologic changes in Parkinson's disease, Huntington's disease, and tardive dyskinesia may elucidate the pathophysiology of these disorders, especially the presence of hypothalamic lesions. There is probably a decrease in PRL concentrations in Parkinson's disease, and there may be an increase in TSH response to TRH stimulation. It is not clear if there is any change in GH concentrations in Parkinson's disease. There appears to be a robust increase in GH concentrations in Huntington's disease, and there may be a small increase in PRL as well. At present no endocrinologic abnormality has been well documented in tardive dyskinesia.",
author = "B. Kirkpatrick and Tamminga, {C. A.}",
year = "1988",
language = "English (US)",
volume = "6",
pages = "159--172",
journal = "Neurologic Clinics",
issn = "0733-8619",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - The endocrinology of extrapyramidal system disorders

AU - Kirkpatrick, B.

AU - Tamminga, C. A.

PY - 1988

Y1 - 1988

N2 - The study of endocrinologic changes in Parkinson's disease, Huntington's disease, and tardive dyskinesia may elucidate the pathophysiology of these disorders, especially the presence of hypothalamic lesions. There is probably a decrease in PRL concentrations in Parkinson's disease, and there may be an increase in TSH response to TRH stimulation. It is not clear if there is any change in GH concentrations in Parkinson's disease. There appears to be a robust increase in GH concentrations in Huntington's disease, and there may be a small increase in PRL as well. At present no endocrinologic abnormality has been well documented in tardive dyskinesia.

AB - The study of endocrinologic changes in Parkinson's disease, Huntington's disease, and tardive dyskinesia may elucidate the pathophysiology of these disorders, especially the presence of hypothalamic lesions. There is probably a decrease in PRL concentrations in Parkinson's disease, and there may be an increase in TSH response to TRH stimulation. It is not clear if there is any change in GH concentrations in Parkinson's disease. There appears to be a robust increase in GH concentrations in Huntington's disease, and there may be a small increase in PRL as well. At present no endocrinologic abnormality has been well documented in tardive dyskinesia.

UR - http://www.scopus.com/inward/record.url?scp=0023905591&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023905591&partnerID=8YFLogxK

M3 - Article

C2 - 2967909

VL - 6

SP - 159

EP - 172

JO - Neurologic Clinics

JF - Neurologic Clinics

SN - 0733-8619

IS - 1

ER -