@article{69fca40ca7f44d56a6a4561b79eb0e38,
title = "The function of ncRNAs in rheumatic diseases",
abstract = "Rheumatic diseases are a group of chronic heterogeneous autoimmune disorders characterized by abnormal regulation of the innate and adaptive immune systems. Despite extensive efforts, the full spectrum of molecular factors that contribute to the pathogenesis of rheumatic diseases remains unclear. ncRNAs can govern gene expression at the transcriptional and post-transcriptional levels in multiple diseases. Recent studies have demonstrated an important role for ncRNAs, such as miRNAs and lncRNAs, in the development of immune cells and rheumatic diseases. Here, we focus on the epigenetic regulatory roles of ncRNAs in the pathogenesis of rheumatic diseases and as biomarkers of disease state.",
keywords = "circular RNA, lncRNA, miRNA, ncRNA, piRNAs, rheumatic diseases",
author = "Weilin Chen and Di Liu and Li, {Quan Zhen} and Honglin Zhu",
note = "Funding Information: This study was funded by grants from Hunan Provincial Natural Science Foundation (2018JJ3823), National Natural Science Foundation of China (81671621) and Fundamental Research Funds for the Central Universities of Central South University (2018zzts247). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Funding Information: This study was funded by grants from Hunan Provincial Natural Science Foundation (2018JJ3823), National Natural Science Foundation of China (81671621) and Fundamental Research Funds for the Central Universities of Central South University (2018zzts247). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. Publisher Copyright: {\textcopyright} 2019 Future Medicine Ltd.",
year = "2019",
doi = "10.2217/epi-2018-0135",
language = "English (US)",
volume = "11",
pages = "821--833",
journal = "Epigenomics",
issn = "1750-1911",
publisher = "Future Medicine Ltd.",
number = "7",
}