TY - JOUR
T1 - The Geometry of Locomotive Behavioral States in C. elegans
AU - Gallagher, Thomas
AU - Bjorness, Theresa
AU - Greene, Robert
AU - You, Young Jai
AU - Avery, Leon
PY - 2013/3/28
Y1 - 2013/3/28
N2 - We develop a new hidden Markov model-based method to analyze C elegans locomotive behavior and use this method to quantitatively characterize behavioral states. In agreement with previous work, we find states corresponding to roaming, dwelling, and quiescence. However, we also find evidence for a continuum of intermediate states. We suggest that roaming, dwelling, and quiescence may best be thought of as extremes which, mixed in any proportion, define the locomotive repertoire of C elegans foraging and feeding behavior.
AB - We develop a new hidden Markov model-based method to analyze C elegans locomotive behavior and use this method to quantitatively characterize behavioral states. In agreement with previous work, we find states corresponding to roaming, dwelling, and quiescence. However, we also find evidence for a continuum of intermediate states. We suggest that roaming, dwelling, and quiescence may best be thought of as extremes which, mixed in any proportion, define the locomotive repertoire of C elegans foraging and feeding behavior.
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U2 - 10.1371/journal.pone.0059865
DO - 10.1371/journal.pone.0059865
M3 - Article
C2 - 23555813
AN - SCOPUS:84875544293
SN - 1932-6203
VL - 8
JO - PloS one
JF - PloS one
IS - 3
M1 - e59865
ER -