The hunt for RNA polymerase II elongation factors: a historical perspective

Ronald C. Conaway; Joan W. Conaway

doi:10.1038/s41594-019-0283-1

The hunt for RNA polymerase II elongation factors: a historical perspective

Ronald C. Conaway, Joan W. Conaway

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this adventure from our vantage point, with a focus on the hunt for factors that regulate elongation by RNA polymerase II.

Original language	English (US)
Pages (from-to)	771-776
Number of pages	6
Journal	Nature Structural and Molecular Biology
Volume	26
Issue number	9
DOIs	https://doi.org/10.1038/s41594-019-0283-1
State	Published - Sep 1 2019
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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title = "The hunt for RNA polymerase II elongation factors: a historical perspective",

abstract = "The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this adventure from our vantage point, with a focus on the hunt for factors that regulate elongation by RNA polymerase II.",

author = "Conaway, {Ronald C.} and Conaway, {Joan W.}",

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AU - Conaway, Joan W.

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N2 - The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this adventure from our vantage point, with a focus on the hunt for factors that regulate elongation by RNA polymerase II.

AB - The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this adventure from our vantage point, with a focus on the hunt for factors that regulate elongation by RNA polymerase II.

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JO - Nature Structural and Molecular Biology

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The hunt for RNA polymerase II elongation factors: a historical perspective

Abstract

ASJC Scopus subject areas

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