The hypothalamic regulation of metabolic adaptations to exercise

T. Fujikawa; C. M. Castorena; S. Lee; J. K. Elmquist

doi:10.1111/jne.12533

The hypothalamic regulation of metabolic adaptations to exercise

T. Fujikawa, C. M. Castorena, S. Lee, J. K. Elmquist

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Our modern lifestyle is characterised by easy access to nutrient dense foods combined with limited physical activity. A sedentary lifestyle is one of several factors that have contributed to the global obesity epidemic and it also predisposes to chronic illnesses such as diabetes and cardiovascular disease. Although many studies have focused on the benefits of exercise in peripheral tissues, the contributions of the central nervous system to these exercise-induced metabolic adaptations are relatively unknown. The present review highlights the role of the ventromedial hypothalamus in regulating the metabolic response to exercise.

Original language	English (US)
Article number	e12533
Journal	Journal of Neuroendocrinology
Volume	29
Issue number	10
DOIs	https://doi.org/10.1111/jne.12533
State	Published - Oct 2017

Keywords

energy expenditure
exercise
hypothalamus
metabolism
ventromedial hypothalamus

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Cellular and Molecular Neuroscience

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10.1111/jne.12533

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title = "The hypothalamic regulation of metabolic adaptations to exercise",

abstract = "Our modern lifestyle is characterised by easy access to nutrient dense foods combined with limited physical activity. A sedentary lifestyle is one of several factors that have contributed to the global obesity epidemic and it also predisposes to chronic illnesses such as diabetes and cardiovascular disease. Although many studies have focused on the benefits of exercise in peripheral tissues, the contributions of the central nervous system to these exercise-induced metabolic adaptations are relatively unknown. The present review highlights the role of the ventromedial hypothalamus in regulating the metabolic response to exercise.",

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AU - Castorena, C. M.

AU - Lee, S.

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AB - Our modern lifestyle is characterised by easy access to nutrient dense foods combined with limited physical activity. A sedentary lifestyle is one of several factors that have contributed to the global obesity epidemic and it also predisposes to chronic illnesses such as diabetes and cardiovascular disease. Although many studies have focused on the benefits of exercise in peripheral tissues, the contributions of the central nervous system to these exercise-induced metabolic adaptations are relatively unknown. The present review highlights the role of the ventromedial hypothalamus in regulating the metabolic response to exercise.

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KW - hypothalamus

KW - metabolism

KW - ventromedial hypothalamus

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The hypothalamic regulation of metabolic adaptations to exercise

Abstract

Keywords

ASJC Scopus subject areas

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