The immunobiology of Acanthamoeba keratitis

Daniel W. Clarke, Jerry Y. Niederkorn

Research output: Contribution to journalShort surveypeer-review

41 Scopus citations


Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals.

Original languageEnglish (US)
Pages (from-to)1400-1405
Number of pages6
JournalMicrobes and Infection
Issue number5
StatePublished - Apr 2006


  • Amoeba
  • Cornea
  • Immunology
  • Keratitis

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases


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