The impact of prenatal bowel dilation on clinical outcomes in neonates with gastroschisis

Hannah G. Piper, Tom Jaksic

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Purpose: In fetuses with gastroschisis, the importance of ultrasonographic bowel dilation remains controversial. The outcome of patients with gastroschisis with and without prenatal bowel dilation is reported. Methods: From 2000 to 2004, 27 neonates with gastroschisis were followed at a single center. Thirteen patients had prenatal ultrasonographic bowel dilation (diameter, ≥6 mm; range, 6-35 mm). Outcomes of those with and without dilation were compared using 2 sample t tests and logistic regression. Results: Time to initiation of enteral nutrition varied significantly between groups (20.4 ± 11.7 days vs 12.5 ± 4.3 days, P < .05). A trend toward a reduced rate of primary closure was seen in those with dilation (23% vs 50%, P = .06). No significant difference was found when considering mortality, gestational age, time in the intensive care unit (ICU), time on parenteral nutrition, or length of stay. Prenatal bowel dilation, a longer ICU stay, and later gestational age independently predicted readmission for bowel obstruction (P < .001). Conclusion: Infants with gastroschisis and prenatal bowel dilation were significantly slower to initiate enteral feeding and tended to have a reduced incidence of primary closure. This did not translate into increased mortality, time on parenteral nutrition, time in the ICU, or length of stay. However, dilation was associated with readmission for bowel obstruction.

Original languageEnglish (US)
Pages (from-to)897-900
Number of pages4
JournalJournal of Pediatric Surgery
Volume41
Issue number5
DOIs
StatePublished - May 1 2006

Fingerprint

Gastroschisis
Dilatation
Newborn Infant
Intensive Care Units
Parenteral Nutrition
Enteral Nutrition
Gestational Age
Length of Stay
Mortality
Fetus
Logistic Models
Incidence

Keywords

  • Bowel dilation
  • Gastroschisis
  • Prenatal ultrasound

ASJC Scopus subject areas

  • Surgery

Cite this

The impact of prenatal bowel dilation on clinical outcomes in neonates with gastroschisis. / Piper, Hannah G.; Jaksic, Tom.

In: Journal of Pediatric Surgery, Vol. 41, No. 5, 01.05.2006, p. 897-900.

Research output: Contribution to journalArticle

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