The increasing frequency of adenocarcinoma of the esophagus

P. J. Hesketh, R. W. Clapp, W. G. Doos, S. J. Spechler

Research output: Contribution to journalArticle

181 Citations (Scopus)

Abstract

Adenocarcinoma of the esophagus has been considered an uncommon tumor, accounting for fewer than 8% of all cases of esophageal cancer. To determine the current frequency of adenocarcinoma of the esophagus, we reviewed data from the tumor registries of the Commonwealth of Massachusetts, the University Hospital (UH), and the Boston VA Medical Center (BVAMC). From 1982 to 1984, 868 esophageal cancers were reported in Massachusetts, of which 231 (27%) were adenocarcinomas. In comparison with squamous cell carcinomas of the esophagus, esophageal adenocarcinomas occurred more frequently in males (P < 0.01) and were uncommon among blacks (P < 0.01). From 1980 to 1986, 262 cases of esophageal cancer were seen at the UH and the BVAMC, of which 81 (31%) were adenocarcinomas. An analysis of the latter group to identify true esophageal adenocarcinomas (tumors confined to the esophagus without gastric involvement) yielded 47 cases. Thus, true esophageal adenocarcinoma accounted for 18% of esophageal malignancies at our hospitals, a frequency threefold to fivefold higher than that found in four prior studies that used comparable anatomic diagnostic criteria. We conclude that adenocarcinoma of the esophagus is now being recognized at a substantially higher frequency than reported in the past.

Original languageEnglish (US)
Pages (from-to)526-530
Number of pages5
JournalCancer
Volume64
Issue number2
StatePublished - 1989

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Adenocarcinoma
Esophageal Neoplasms
Neoplasms
Esophagus
Registries
Stomach
Adenocarcinoma Of Esophagus

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Hesketh, P. J., Clapp, R. W., Doos, W. G., & Spechler, S. J. (1989). The increasing frequency of adenocarcinoma of the esophagus. Cancer, 64(2), 526-530.

The increasing frequency of adenocarcinoma of the esophagus. / Hesketh, P. J.; Clapp, R. W.; Doos, W. G.; Spechler, S. J.

In: Cancer, Vol. 64, No. 2, 1989, p. 526-530.

Research output: Contribution to journalArticle

Hesketh, PJ, Clapp, RW, Doos, WG & Spechler, SJ 1989, 'The increasing frequency of adenocarcinoma of the esophagus', Cancer, vol. 64, no. 2, pp. 526-530.
Hesketh PJ, Clapp RW, Doos WG, Spechler SJ. The increasing frequency of adenocarcinoma of the esophagus. Cancer. 1989;64(2):526-530.
Hesketh, P. J. ; Clapp, R. W. ; Doos, W. G. ; Spechler, S. J. / The increasing frequency of adenocarcinoma of the esophagus. In: Cancer. 1989 ; Vol. 64, No. 2. pp. 526-530.
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