The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies

Orhan Bukulmez

doi:10.1007/978-3-030-23235-1_10

The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In order to increase the oocyte yield from a single in vitro fertilization (IVF) cycle, controlled ovarian stimulation (COS) protocols were developed. Increased daily doses of follicle-stimulating hormone (FSH) products in conventional COS protocols brought concerns about their association with ovarian hyperstimulation syndrome, multiple pregnancies due to the transfer of increased number of embryos to achieve pregnancy, increased embryonic aneuploidy, and inferior IVF outcomes. This leads to revisiting milder stimulation protocols for IVF. The International Society for Mild Approaches in Assisted Reproduction (ISMAAR) brought the definition for mild stimulation. Gentle approaches to IVF including natural cycle and mild and minimal stimulation protocols found acceptance especially in women with expected poor ovarian response, mostly due to diminished ovarian reserve and advanced reproductive age.

Original language	English (US)
Title of host publication	Diminished Ovarian Reserve and Assisted Reproductive Technologies
Subtitle of host publication	Current Research and Clinical Management
Publisher	Springer International Publishing
Pages	141-149
Number of pages	9
ISBN (Electronic)	9783030232351
ISBN (Print)	9783030232344
DOIs	https://doi.org/10.1007/978-3-030-23235-1_10
State	Published - Jan 1 2019

Keywords

Advanced reproductive age
Assisted reproductive technology
ISMAAR
IVF
Mild stimulation
Poor ovarian response

ASJC Scopus subject areas

General Health Professions
General Medicine

Access to Document

10.1007/978-3-030-23235-1_10

Cite this

Bukulmez, O. (2019). The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies. In Diminished Ovarian Reserve and Assisted Reproductive Technologies: Current Research and Clinical Management (pp. 141-149). Springer International Publishing. https://doi.org/10.1007/978-3-030-23235-1_10

The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies. / Bukulmez, Orhan.
Diminished Ovarian Reserve and Assisted Reproductive Technologies: Current Research and Clinical Management. Springer International Publishing, 2019. p. 141-149.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Bukulmez, O 2019, The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies. in Diminished Ovarian Reserve and Assisted Reproductive Technologies: Current Research and Clinical Management. Springer International Publishing, pp. 141-149. https://doi.org/10.1007/978-3-030-23235-1_10

Bukulmez O. The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies. In Diminished Ovarian Reserve and Assisted Reproductive Technologies: Current Research and Clinical Management. Springer International Publishing. 2019. p. 141-149 doi: 10.1007/978-3-030-23235-1_10

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The international society for mild approaches in assisted reproduction (ISMAAR) definitions for mild stimulation and their rationale for assisted reproductive technologies

Abstract

Keywords

ASJC Scopus subject areas

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