The ITMIG/IASLC thymic epithelial tumors staging project: A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classification of malignant tumors

Faiz Y. Bhora, David J. Chen, Frank C. Detterbeck, Hisao Asamura, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Kazuya Kondo, Marco Lucchi, Mirella Marino, Edith M. Marom, Andrew G. Nicholson, Meinoshin Okumura, Enrico Ruffini, Paul Van Schil, Peter Goldstraw, Ramón Rami-Porta, David BallDavid Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, John Crowley, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Dorothy Giroux, Fergus Gleeson, Patti Groome, Catherine Kennedy, Young Tae Kim, Laura Kingsbury, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Jan Van Meerbeeck, Alan Mitchell, Takashi Nakano, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Valerie Rusch, Nagahiro Saijo, Jean Paul Sculier, Lynn Shemanski, Kelly Stratton, Kenji Suzuki, Yuji Tachimori, Charles F. Thomas, William Travis, Ming S. Tsao, Andrew Turrisi, Johan Vansteenkiste, Hirokazu Watanabe, Yi Long Wu, Paul Baas, Jeremy Erasmus, Seiki Hasegawa, Kouki Inai, Kemp Kernstine, Hedy Kindler, Lee Krug, Kristiaan Nackaerts, Harvey Pass, David Rice, Eugene Blackstone

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Although the presence of nodal disease is prognostic in thymic malignancy, the significance of the extent of nodal disease has yet to be defined. Lymph node dissection has not been routinely performed, and there is currently no node map defined for thymic malignancy. To establish a universal language for reporting as well as characterize the staging of this disease more accurately, an empiric node map is proposed here. This was developed using prior classification systems, series reporting specifics of nodal involvement, anatomical studies of lymphatic drainage, and preexisting node maps of the chest as defined by the International Association for the Study of Lung Cancer and the neck as defined by the American Academy of Otolaryngology - Head and Neck Surgery and the American Society for Head and Neck Surgery. The development of this node map was a joint effort by the International Thymic Malignancy Interest Group and the Thymic Domain of the IASLC Staging and Prognostic Factors Committee. It was reviewed and subsequently approved by the members of ITMIG. This map will be used as an adjunct to define node staging as part of a universal stage classification for thymic malignancy. As more data are gathered using definitions set forth by this node map, a revision may be undertaken in the future.

Original languageEnglish (US)
Pages (from-to)S88-S96
JournalJournal of Thoracic Oncology
Volume9
Issue number9
StatePublished - Sep 1 2014

Fingerprint

Neoplasm Staging
Lymph Nodes
Neck
Neoplasms
Head
Public Opinion
Otolaryngology
Lymph Node Excision
Drainage
Language
Thorax
Thymic epithelial tumor

Keywords

  • Anterior mediastinal node map
  • Anterior mediastinal nodes
  • ITMIG
  • Thymic carcinoma
  • Thymic malignancy
  • Thymic neuroendocrine tumor
  • Thymic node map
  • Thymoma

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

The ITMIG/IASLC thymic epithelial tumors staging project : A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classification of malignant tumors. / Bhora, Faiz Y.; Chen, David J.; Detterbeck, Frank C.; Asamura, Hisao; Falkson, Conrad; Filosso, Pier Luigi; Giaccone, Giuseppe; Huang, James; Kim, Jhingook; Kondo, Kazuya; Lucchi, Marco; Marino, Mirella; Marom, Edith M.; Nicholson, Andrew G.; Okumura, Meinoshin; Ruffini, Enrico; Van Schil, Paul; Goldstraw, Peter; Rami-Porta, Ramón; Ball, David; Beer, David; Beyruti, Ricardo; Bolejack, Vanessa; Chansky, Kari; Crowley, John; Eberhardt, Wilfried Ernst Erich; Edwards, John; Galateau-Sallé, Françoise; Giroux, Dorothy; Gleeson, Fergus; Groome, Patti; Kennedy, Catherine; Kim, Young Tae; Kingsbury, Laura; Kondo, Haruhiko; Krasnik, Mark; Kubota, Kaoru; Lerut, Antoon; Lyons, Gustavo; Van Meerbeeck, Jan; Mitchell, Alan; Nakano, Takashi; Nowak, Anna; Peake, Michael; Rice, Thomas; Rosenzweig, Kenneth; Rusch, Valerie; Saijo, Nagahiro; Sculier, Jean Paul; Shemanski, Lynn; Stratton, Kelly; Suzuki, Kenji; Tachimori, Yuji; Thomas, Charles F.; Travis, William; Tsao, Ming S.; Turrisi, Andrew; Vansteenkiste, Johan; Watanabe, Hirokazu; Wu, Yi Long; Baas, Paul; Erasmus, Jeremy; Hasegawa, Seiki; Inai, Kouki; Kernstine, Kemp; Kindler, Hedy; Krug, Lee; Nackaerts, Kristiaan; Pass, Harvey; Rice, David; Blackstone, Eugene.

In: Journal of Thoracic Oncology, Vol. 9, No. 9, 01.09.2014, p. S88-S96.

Research output: Contribution to journalArticle

Bhora, FY, Chen, DJ, Detterbeck, FC, Asamura, H, Falkson, C, Filosso, PL, Giaccone, G, Huang, J, Kim, J, Kondo, K, Lucchi, M, Marino, M, Marom, EM, Nicholson, AG, Okumura, M, Ruffini, E, Van Schil, P, Goldstraw, P, Rami-Porta, R, Ball, D, Beer, D, Beyruti, R, Bolejack, V, Chansky, K, Crowley, J, Eberhardt, WEE, Edwards, J, Galateau-Sallé, F, Giroux, D, Gleeson, F, Groome, P, Kennedy, C, Kim, YT, Kingsbury, L, Kondo, H, Krasnik, M, Kubota, K, Lerut, A, Lyons, G, Van Meerbeeck, J, Mitchell, A, Nakano, T, Nowak, A, Peake, M, Rice, T, Rosenzweig, K, Rusch, V, Saijo, N, Sculier, JP, Shemanski, L, Stratton, K, Suzuki, K, Tachimori, Y, Thomas, CF, Travis, W, Tsao, MS, Turrisi, A, Vansteenkiste, J, Watanabe, H, Wu, YL, Baas, P, Erasmus, J, Hasegawa, S, Inai, K, Kernstine, K, Kindler, H, Krug, L, Nackaerts, K, Pass, H, Rice, D & Blackstone, E 2014, 'The ITMIG/IASLC thymic epithelial tumors staging project: A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classification of malignant tumors', Journal of Thoracic Oncology, vol. 9, no. 9, pp. S88-S96.
Bhora, Faiz Y. ; Chen, David J. ; Detterbeck, Frank C. ; Asamura, Hisao ; Falkson, Conrad ; Filosso, Pier Luigi ; Giaccone, Giuseppe ; Huang, James ; Kim, Jhingook ; Kondo, Kazuya ; Lucchi, Marco ; Marino, Mirella ; Marom, Edith M. ; Nicholson, Andrew G. ; Okumura, Meinoshin ; Ruffini, Enrico ; Van Schil, Paul ; Goldstraw, Peter ; Rami-Porta, Ramón ; Ball, David ; Beer, David ; Beyruti, Ricardo ; Bolejack, Vanessa ; Chansky, Kari ; Crowley, John ; Eberhardt, Wilfried Ernst Erich ; Edwards, John ; Galateau-Sallé, Françoise ; Giroux, Dorothy ; Gleeson, Fergus ; Groome, Patti ; Kennedy, Catherine ; Kim, Young Tae ; Kingsbury, Laura ; Kondo, Haruhiko ; Krasnik, Mark ; Kubota, Kaoru ; Lerut, Antoon ; Lyons, Gustavo ; Van Meerbeeck, Jan ; Mitchell, Alan ; Nakano, Takashi ; Nowak, Anna ; Peake, Michael ; Rice, Thomas ; Rosenzweig, Kenneth ; Rusch, Valerie ; Saijo, Nagahiro ; Sculier, Jean Paul ; Shemanski, Lynn ; Stratton, Kelly ; Suzuki, Kenji ; Tachimori, Yuji ; Thomas, Charles F. ; Travis, William ; Tsao, Ming S. ; Turrisi, Andrew ; Vansteenkiste, Johan ; Watanabe, Hirokazu ; Wu, Yi Long ; Baas, Paul ; Erasmus, Jeremy ; Hasegawa, Seiki ; Inai, Kouki ; Kernstine, Kemp ; Kindler, Hedy ; Krug, Lee ; Nackaerts, Kristiaan ; Pass, Harvey ; Rice, David ; Blackstone, Eugene. / The ITMIG/IASLC thymic epithelial tumors staging project : A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classification of malignant tumors. In: Journal of Thoracic Oncology. 2014 ; Vol. 9, No. 9. pp. S88-S96.
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abstract = "Although the presence of nodal disease is prognostic in thymic malignancy, the significance of the extent of nodal disease has yet to be defined. Lymph node dissection has not been routinely performed, and there is currently no node map defined for thymic malignancy. To establish a universal language for reporting as well as characterize the staging of this disease more accurately, an empiric node map is proposed here. This was developed using prior classification systems, series reporting specifics of nodal involvement, anatomical studies of lymphatic drainage, and preexisting node maps of the chest as defined by the International Association for the Study of Lung Cancer and the neck as defined by the American Academy of Otolaryngology - Head and Neck Surgery and the American Society for Head and Neck Surgery. The development of this node map was a joint effort by the International Thymic Malignancy Interest Group and the Thymic Domain of the IASLC Staging and Prognostic Factors Committee. It was reviewed and subsequently approved by the members of ITMIG. This map will be used as an adjunct to define node staging as part of a universal stage classification for thymic malignancy. As more data are gathered using definitions set forth by this node map, a revision may be undertaken in the future.",
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T2 - A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classification of malignant tumors

AU - Bhora, Faiz Y.

AU - Chen, David J.

AU - Detterbeck, Frank C.

AU - Asamura, Hisao

AU - Falkson, Conrad

AU - Filosso, Pier Luigi

AU - Giaccone, Giuseppe

AU - Huang, James

AU - Kim, Jhingook

AU - Kondo, Kazuya

AU - Lucchi, Marco

AU - Marino, Mirella

AU - Marom, Edith M.

AU - Nicholson, Andrew G.

AU - Okumura, Meinoshin

AU - Ruffini, Enrico

AU - Van Schil, Paul

AU - Goldstraw, Peter

AU - Rami-Porta, Ramón

AU - Ball, David

AU - Beer, David

AU - Beyruti, Ricardo

AU - Bolejack, Vanessa

AU - Chansky, Kari

AU - Crowley, John

AU - Eberhardt, Wilfried Ernst Erich

AU - Edwards, John

AU - Galateau-Sallé, Françoise

AU - Giroux, Dorothy

AU - Gleeson, Fergus

AU - Groome, Patti

AU - Kennedy, Catherine

AU - Kim, Young Tae

AU - Kingsbury, Laura

AU - Kondo, Haruhiko

AU - Krasnik, Mark

AU - Kubota, Kaoru

AU - Lerut, Antoon

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AU - Rusch, Valerie

AU - Saijo, Nagahiro

AU - Sculier, Jean Paul

AU - Shemanski, Lynn

AU - Stratton, Kelly

AU - Suzuki, Kenji

AU - Tachimori, Yuji

AU - Thomas, Charles F.

AU - Travis, William

AU - Tsao, Ming S.

AU - Turrisi, Andrew

AU - Vansteenkiste, Johan

AU - Watanabe, Hirokazu

AU - Wu, Yi Long

AU - Baas, Paul

AU - Erasmus, Jeremy

AU - Hasegawa, Seiki

AU - Inai, Kouki

AU - Kernstine, Kemp

AU - Kindler, Hedy

AU - Krug, Lee

AU - Nackaerts, Kristiaan

AU - Pass, Harvey

AU - Rice, David

AU - Blackstone, Eugene

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KW - Anterior mediastinal nodes

KW - ITMIG

KW - Thymic carcinoma

KW - Thymic malignancy

KW - Thymic neuroendocrine tumor

KW - Thymic node map

KW - Thymoma

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