The joint associations of multiple risk factors with the occurrence of nosocomial infection

Thomas M. Hooton, Robert W. Haley, David H. Culver, John W. White, W. Meade Morgan, Raymond J. Carroll

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

To compare nosocomial infection rates estimated in different time periods or in different hospitals, it is necessary to control for differences in the distribution of factors that substantially influence a patient's susceptibility to infection. To evaluate the associations of multiple risk factors with the occurrence of infection at each of four major sites and to develop composite measures for use in controlling for differences in the distribution of risk among groups of patients, we used a multivariate categorical data analysis technique to study the infection experience of 169,518 patients admitted in 1970 to the 338 hospitals studied in the Study on the Efficacy of Nosocomial Infection Control (SENIC Project). The relative importance of risk factors and their complex interactions varied by site. The factors found to be highly important for one or more sites were duration of urinary catheterization, the patients' intrinsic risk as reflected in their diagnoses and types of surgical procedures, duration of preoperative hospitalization, duration of operation, anatomic location of surgical procedure, previous infection and steroid or immunosuppressive therapy. Site-specific risk strata and estimates of each patient's probability of acquiring infection were developed from these data for use in future SENIC analyses.

Original languageEnglish (US)
Pages (from-to)960-970
Number of pages11
JournalThe American journal of medicine
Volume70
Issue number4
DOIs
StatePublished - 1981

Fingerprint

Cross Infection
Infection
Urinary Catheterization
Preoperative Care
Immunosuppressive Agents
Infection Control
Hospitalization
Steroids
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

The joint associations of multiple risk factors with the occurrence of nosocomial infection. / Hooton, Thomas M.; Haley, Robert W.; Culver, David H.; White, John W.; Morgan, W. Meade; Carroll, Raymond J.

In: The American journal of medicine, Vol. 70, No. 4, 1981, p. 960-970.

Research output: Contribution to journalArticle

Hooton, Thomas M. ; Haley, Robert W. ; Culver, David H. ; White, John W. ; Morgan, W. Meade ; Carroll, Raymond J. / The joint associations of multiple risk factors with the occurrence of nosocomial infection. In: The American journal of medicine. 1981 ; Vol. 70, No. 4. pp. 960-970.
@article{fb5cfcb7814741cba5d21ac9051cf9d9,
title = "The joint associations of multiple risk factors with the occurrence of nosocomial infection",
abstract = "To compare nosocomial infection rates estimated in different time periods or in different hospitals, it is necessary to control for differences in the distribution of factors that substantially influence a patient's susceptibility to infection. To evaluate the associations of multiple risk factors with the occurrence of infection at each of four major sites and to develop composite measures for use in controlling for differences in the distribution of risk among groups of patients, we used a multivariate categorical data analysis technique to study the infection experience of 169,518 patients admitted in 1970 to the 338 hospitals studied in the Study on the Efficacy of Nosocomial Infection Control (SENIC Project). The relative importance of risk factors and their complex interactions varied by site. The factors found to be highly important for one or more sites were duration of urinary catheterization, the patients' intrinsic risk as reflected in their diagnoses and types of surgical procedures, duration of preoperative hospitalization, duration of operation, anatomic location of surgical procedure, previous infection and steroid or immunosuppressive therapy. Site-specific risk strata and estimates of each patient's probability of acquiring infection were developed from these data for use in future SENIC analyses.",
author = "Hooton, {Thomas M.} and Haley, {Robert W.} and Culver, {David H.} and White, {John W.} and Morgan, {W. Meade} and Carroll, {Raymond J.}",
year = "1981",
doi = "10.1016/0002-9343(81)90562-3",
language = "English (US)",
volume = "70",
pages = "960--970",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - The joint associations of multiple risk factors with the occurrence of nosocomial infection

AU - Hooton, Thomas M.

AU - Haley, Robert W.

AU - Culver, David H.

AU - White, John W.

AU - Morgan, W. Meade

AU - Carroll, Raymond J.

PY - 1981

Y1 - 1981

N2 - To compare nosocomial infection rates estimated in different time periods or in different hospitals, it is necessary to control for differences in the distribution of factors that substantially influence a patient's susceptibility to infection. To evaluate the associations of multiple risk factors with the occurrence of infection at each of four major sites and to develop composite measures for use in controlling for differences in the distribution of risk among groups of patients, we used a multivariate categorical data analysis technique to study the infection experience of 169,518 patients admitted in 1970 to the 338 hospitals studied in the Study on the Efficacy of Nosocomial Infection Control (SENIC Project). The relative importance of risk factors and their complex interactions varied by site. The factors found to be highly important for one or more sites were duration of urinary catheterization, the patients' intrinsic risk as reflected in their diagnoses and types of surgical procedures, duration of preoperative hospitalization, duration of operation, anatomic location of surgical procedure, previous infection and steroid or immunosuppressive therapy. Site-specific risk strata and estimates of each patient's probability of acquiring infection were developed from these data for use in future SENIC analyses.

AB - To compare nosocomial infection rates estimated in different time periods or in different hospitals, it is necessary to control for differences in the distribution of factors that substantially influence a patient's susceptibility to infection. To evaluate the associations of multiple risk factors with the occurrence of infection at each of four major sites and to develop composite measures for use in controlling for differences in the distribution of risk among groups of patients, we used a multivariate categorical data analysis technique to study the infection experience of 169,518 patients admitted in 1970 to the 338 hospitals studied in the Study on the Efficacy of Nosocomial Infection Control (SENIC Project). The relative importance of risk factors and their complex interactions varied by site. The factors found to be highly important for one or more sites were duration of urinary catheterization, the patients' intrinsic risk as reflected in their diagnoses and types of surgical procedures, duration of preoperative hospitalization, duration of operation, anatomic location of surgical procedure, previous infection and steroid or immunosuppressive therapy. Site-specific risk strata and estimates of each patient's probability of acquiring infection were developed from these data for use in future SENIC analyses.

UR - http://www.scopus.com/inward/record.url?scp=0019495647&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019495647&partnerID=8YFLogxK

U2 - 10.1016/0002-9343(81)90562-3

DO - 10.1016/0002-9343(81)90562-3

M3 - Article

C2 - 7211932

AN - SCOPUS:0019495647

VL - 70

SP - 960

EP - 970

JO - American Journal of Medicine

JF - American Journal of Medicine

SN - 0002-9343

IS - 4

ER -