The kidney stone and increased water intake trial in steel workers: results from a pilot study

Yair Lotan, Jodi Antonelli, Inmaculada Buendia Jiménez, Hakam Gharbi, Ron Herring, Allison Beaver, Aphrihl Dennis, Dendra von Merveldt, Suzie Carter, Adam Cohen, John Poindexter, Orson W Moe, Margaret S Pearle

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift (‘post-shift’) spot urine osmolality and 24-h urinary stone risk parameters. 100 volunteers were recruited from Gerdau Midlothian steel mill in Texas on 11/14/14 and 12/5/14. Clinical data were recorded and post-shift spot urine sample was used to measure urine osmolality. Participants were invited to submit a 24-h urine sample within 4 weeks of enrollment. The mean age was 41 years and 95 % were men. The majority of subjects were white (75 %), followed by 10 % Hispanic and 9 % black. The mean body mass index was 30.1 kg/m2 and overall 16 % had a past history of stone disease. Mean post-shift urine spot osmolality was 704.5 mOsm (169–1165 mOsm) and was >800 and >700 mOsm in 39 and 57 %, respectively. Among 59 24-h urines samples, the mean volume was 1.89 ± 0.92 l/day, with 56 % <2 L and 17 % <1 L. Elevated levels of urinary analytes were found in 29 % of subjects for calcium (>250 mg/TV), 39 % for uric acid (>700 mg/TV), 25 % for oxalate (>45 mg/TV) and 50 % for sodium (>200 meq/TV). The prevalence of stone disease in this population of steel workers was higher than the published prevalence of stone disease in the general population. A significant number of workers had concentrated post-shift and 24-h urines and elevated levels of urinary analytes.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalUrolithiasis
DOIs
StateAccepted/In press - May 26 2016

Fingerprint

Kidney Calculi
Steel
Drinking
Urine
Osmolar Concentration
Urinary Calculi
Oxalates
Primary Prevention
Uric Acid
Dehydration
Hispanic Americans
Population
Volunteers
Body Mass Index
Sodium

Keywords

  • Hydration
  • Kidney stones
  • Prevention
  • Steel workers

ASJC Scopus subject areas

  • Urology

Cite this

The kidney stone and increased water intake trial in steel workers : results from a pilot study. / Lotan, Yair; Antonelli, Jodi; Jiménez, Inmaculada Buendia; Gharbi, Hakam; Herring, Ron; Beaver, Allison; Dennis, Aphrihl; von Merveldt, Dendra; Carter, Suzie; Cohen, Adam; Poindexter, John; Moe, Orson W; Pearle, Margaret S.

In: Urolithiasis, 26.05.2016, p. 1-7.

Research output: Contribution to journalArticle

Lotan, Y, Antonelli, J, Jiménez, IB, Gharbi, H, Herring, R, Beaver, A, Dennis, A, von Merveldt, D, Carter, S, Cohen, A, Poindexter, J, Moe, OW & Pearle, MS 2016, 'The kidney stone and increased water intake trial in steel workers: results from a pilot study', Urolithiasis, pp. 1-7. https://doi.org/10.1007/s00240-016-0892-7
Lotan, Yair ; Antonelli, Jodi ; Jiménez, Inmaculada Buendia ; Gharbi, Hakam ; Herring, Ron ; Beaver, Allison ; Dennis, Aphrihl ; von Merveldt, Dendra ; Carter, Suzie ; Cohen, Adam ; Poindexter, John ; Moe, Orson W ; Pearle, Margaret S. / The kidney stone and increased water intake trial in steel workers : results from a pilot study. In: Urolithiasis. 2016 ; pp. 1-7.
@article{00e6570dd3bf45418b9eab3f3c308750,
title = "The kidney stone and increased water intake trial in steel workers: results from a pilot study",
abstract = "Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift (‘post-shift’) spot urine osmolality and 24-h urinary stone risk parameters. 100 volunteers were recruited from Gerdau Midlothian steel mill in Texas on 11/14/14 and 12/5/14. Clinical data were recorded and post-shift spot urine sample was used to measure urine osmolality. Participants were invited to submit a 24-h urine sample within 4 weeks of enrollment. The mean age was 41 years and 95 {\%} were men. The majority of subjects were white (75 {\%}), followed by 10 {\%} Hispanic and 9 {\%} black. The mean body mass index was 30.1 kg/m2 and overall 16 {\%} had a past history of stone disease. Mean post-shift urine spot osmolality was 704.5 mOsm (169–1165 mOsm) and was >800 and >700 mOsm in 39 and 57 {\%}, respectively. Among 59 24-h urines samples, the mean volume was 1.89 ± 0.92 l/day, with 56 {\%} <2 L and 17 {\%} <1 L. Elevated levels of urinary analytes were found in 29 {\%} of subjects for calcium (>250 mg/TV), 39 {\%} for uric acid (>700 mg/TV), 25 {\%} for oxalate (>45 mg/TV) and 50 {\%} for sodium (>200 meq/TV). The prevalence of stone disease in this population of steel workers was higher than the published prevalence of stone disease in the general population. A significant number of workers had concentrated post-shift and 24-h urines and elevated levels of urinary analytes.",
keywords = "Hydration, Kidney stones, Prevention, Steel workers",
author = "Yair Lotan and Jodi Antonelli and Jim{\'e}nez, {Inmaculada Buendia} and Hakam Gharbi and Ron Herring and Allison Beaver and Aphrihl Dennis and {von Merveldt}, Dendra and Suzie Carter and Adam Cohen and John Poindexter and Moe, {Orson W} and Pearle, {Margaret S}",
year = "2016",
month = "5",
day = "26",
doi = "10.1007/s00240-016-0892-7",
language = "English (US)",
pages = "1--7",
journal = "Urolithiasis",
issn = "2194-7228",
publisher = "Springer Verlag",

}

TY - JOUR

T1 - The kidney stone and increased water intake trial in steel workers

T2 - results from a pilot study

AU - Lotan, Yair

AU - Antonelli, Jodi

AU - Jiménez, Inmaculada Buendia

AU - Gharbi, Hakam

AU - Herring, Ron

AU - Beaver, Allison

AU - Dennis, Aphrihl

AU - von Merveldt, Dendra

AU - Carter, Suzie

AU - Cohen, Adam

AU - Poindexter, John

AU - Moe, Orson W

AU - Pearle, Margaret S

PY - 2016/5/26

Y1 - 2016/5/26

N2 - Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift (‘post-shift’) spot urine osmolality and 24-h urinary stone risk parameters. 100 volunteers were recruited from Gerdau Midlothian steel mill in Texas on 11/14/14 and 12/5/14. Clinical data were recorded and post-shift spot urine sample was used to measure urine osmolality. Participants were invited to submit a 24-h urine sample within 4 weeks of enrollment. The mean age was 41 years and 95 % were men. The majority of subjects were white (75 %), followed by 10 % Hispanic and 9 % black. The mean body mass index was 30.1 kg/m2 and overall 16 % had a past history of stone disease. Mean post-shift urine spot osmolality was 704.5 mOsm (169–1165 mOsm) and was >800 and >700 mOsm in 39 and 57 %, respectively. Among 59 24-h urines samples, the mean volume was 1.89 ± 0.92 l/day, with 56 % <2 L and 17 % <1 L. Elevated levels of urinary analytes were found in 29 % of subjects for calcium (>250 mg/TV), 39 % for uric acid (>700 mg/TV), 25 % for oxalate (>45 mg/TV) and 50 % for sodium (>200 meq/TV). The prevalence of stone disease in this population of steel workers was higher than the published prevalence of stone disease in the general population. A significant number of workers had concentrated post-shift and 24-h urines and elevated levels of urinary analytes.

AB - Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift (‘post-shift’) spot urine osmolality and 24-h urinary stone risk parameters. 100 volunteers were recruited from Gerdau Midlothian steel mill in Texas on 11/14/14 and 12/5/14. Clinical data were recorded and post-shift spot urine sample was used to measure urine osmolality. Participants were invited to submit a 24-h urine sample within 4 weeks of enrollment. The mean age was 41 years and 95 % were men. The majority of subjects were white (75 %), followed by 10 % Hispanic and 9 % black. The mean body mass index was 30.1 kg/m2 and overall 16 % had a past history of stone disease. Mean post-shift urine spot osmolality was 704.5 mOsm (169–1165 mOsm) and was >800 and >700 mOsm in 39 and 57 %, respectively. Among 59 24-h urines samples, the mean volume was 1.89 ± 0.92 l/day, with 56 % <2 L and 17 % <1 L. Elevated levels of urinary analytes were found in 29 % of subjects for calcium (>250 mg/TV), 39 % for uric acid (>700 mg/TV), 25 % for oxalate (>45 mg/TV) and 50 % for sodium (>200 meq/TV). The prevalence of stone disease in this population of steel workers was higher than the published prevalence of stone disease in the general population. A significant number of workers had concentrated post-shift and 24-h urines and elevated levels of urinary analytes.

KW - Hydration

KW - Kidney stones

KW - Prevention

KW - Steel workers

UR - http://www.scopus.com/inward/record.url?scp=84969983964&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84969983964&partnerID=8YFLogxK

U2 - 10.1007/s00240-016-0892-7

DO - 10.1007/s00240-016-0892-7

M3 - Article

C2 - 27228999

AN - SCOPUS:84969983964

SP - 1

EP - 7

JO - Urolithiasis

JF - Urolithiasis

SN - 2194-7228

ER -