The LIPID maps approach to lipidomics

Edward A. Dennis, H. Alex Brown, Raymond A. Deems, Christopher K. Glass, Alfred H. Merrill, Robert C. Murphy, Christian R.H. Raetz, Walter Shaw, Shankar Subramaniam, David W Russell, Michael S. Van Nieuwenhze, Stephen H. White, Joseph L. Witztum, John Wooley

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Scopus citations

Abstract

A five-year, large-scale collaborative “Glue Grant” (funds providing the “glue” to bring investigators together, allowing them to work interactively) was funded by the National Institute of General Medical Sciences (NIGMS) in August 2003 to develop a LIPID Metabolites and Pathways Strategy, known as LIPID MAPS. The goals of the LIPID MAPS Consortium are: (1) to separate and detect all of the lipids in a specific cell and to discover and characterize novel lipids that may be present, (2) to quantitate each of the lipid metabolites present and determine the changes in their levels and locations during cellular function, and (3) to define biosynthetic pathways for each lipid and develop lipid maps that define interaction networks.

Original languageEnglish (US)
Title of host publicationFunctional Lipidomics
PublisherCRC Press
Pages1-15
Number of pages15
ISBN (Electronic)9781420027655
ISBN (Print)9781574444674
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Agricultural and Biological Sciences(all)
  • Medicine(all)

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    Dennis, E. A., Alex Brown, H., Deems, R. A., Glass, C. K., Merrill, A. H., Murphy, R. C., Raetz, C. R. H., Shaw, W., Subramaniam, S., Russell, D. W., Van Nieuwenhze, M. S., White, S. H., Witztum, J. L., & Wooley, J. (2005). The LIPID maps approach to lipidomics. In Functional Lipidomics (pp. 1-15). CRC Press. https://doi.org/10.1201/9781420027655