The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress

Rilee D. Zeinert, Hamid Baniasadi, Benjamin P. Tu, Peter Chien

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Competition between misfolded and natively folded substrates for a limited pool of the highly conserved Lon protease governs stress adaptation.

Original languageEnglish (US)
Pages (from-to)758-767.e6
JournalMolecular cell
Volume79
Issue number5
DOIs
StatePublished - Sep 3 2020

Keywords

  • AAA+ protease
  • chaperone titration
  • proteotoxic stress
  • quality control
  • transposon sequencing

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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