O mekhanizmakh izmeneniǐ koronarnogo sosudistogo soprotivleniia pri anafilakticheskom shoke.

Translated title of the contribution: The mechanisms of the changes in coronary vascular resistance in anaphylactic shock

A. A. Moǐbenko, L. A. Grabovskiǐ, V. N. Kotsiuruba, V. N. Bulakh, L. V. Tumanovskaia, V. I. Azarov, I. A. Butovich

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Anaphylactic shock decreased the coronary perfusion pressure, systemic arterial pressure and cardiac output in anesthetised dogs. After combined inhibition of cyclo-oxygenase and lipoxygenase with linoleate-hydroxamic acid, the anaphylactic coronary constriction and morphological cardiac lesions were considerably diminished. Activation of the lipoxygenase pathway seems to play a major role in development of the coronary constriction in anaphylaxis.

Translated title of the contributionThe mechanisms of the changes in coronary vascular resistance in anaphylactic shock
Original languageRussian
Pages (from-to)77-82
Number of pages6
JournalFiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk
Volume80
Issue number2
StatePublished - Feb 1 1994

ASJC Scopus subject areas

  • Physiology

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    Moǐbenko, A. A., Grabovskiǐ, L. A., Kotsiuruba, V. N., Bulakh, V. N., Tumanovskaia, L. V., Azarov, V. I., & Butovich, I. A. (1994). O mekhanizmakh izmeneniǐ koronarnogo sosudistogo soprotivleniia pri anafilakticheskom shoke. Fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk, 80(2), 77-82.