The metabolic clearance rate of dehydroisoandrosterone sulfate. III. The effect of thiazide diuretics in normal and future pre-eclamptic pregnancies

N. F. Gant; J. D. Madden; P. K. Siiteri; P. C. MacDonald

doi:10.1016/0002-9378(75)90521-9

The metabolic clearance rate of dehydroisoandrosterone sulfate. III. The effect of thiazide diuretics in normal and future pre-eclamptic pregnancies

N. F. Gant, J. D. Madden, P. K. Siiteri, P. C. MacDonald

Obstetrics & Gynecology

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

The present study reports that the metabolic clearance rate of dehydroisoandrosterone sulfate (MCR_DS) is decreased by thiazide diuretics during normal and future pre-eclamptic pregnancies. This observation supports the thesis that diuretics represent a potential hazard to the fetus by decreasing placental perfusion.

Original language	English (US)
Pages (from-to)	159-163
Number of pages	5
Journal	American journal of obstetrics and gynecology
Volume	123
Issue number	2
DOIs	https://doi.org/10.1016/0002-9378(75)90521-9
State	Published - Sep 15 1975

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/0002-9378(75)90521-9

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abstract = "The present study reports that the metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) is decreased by thiazide diuretics during normal and future pre-eclamptic pregnancies. This observation supports the thesis that diuretics represent a potential hazard to the fetus by decreasing placental perfusion.",

author = "Gant, {N. F.} and Madden, {J. D.} and Siiteri, {P. K.} and MacDonald, {P. C.}",

note = "Funding Information: This study was su&@otied in fart by United States Public Health Service Grants HD 00107 and HD 08360.",

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AU - Siiteri, P. K.

AU - MacDonald, P. C.

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AB - The present study reports that the metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) is decreased by thiazide diuretics during normal and future pre-eclamptic pregnancies. This observation supports the thesis that diuretics represent a potential hazard to the fetus by decreasing placental perfusion.

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The metabolic clearance rate of dehydroisoandrosterone sulfate. III. The effect of thiazide diuretics in normal and future pre-eclamptic pregnancies

Abstract

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