The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells

Medicine & Life Sciences

• 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 100%
• Methoxychlor 81%
• Cholesterol 35%
• Progesterone 31%
• Theca Cells 20%
• Androgen Receptors 15%
• Estrogen Receptors 13%
• Fulvestrant 12%
• Cultured Cells 12%
• 4-tert-octylphenol 8%
• vinclozolin 8%
• 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one 8%
• Adrenodoxin 8%
• hydroxyflutamide 8%
• Ferredoxin-NADP Reductase 8%
• Cholesterol Side-Chain Cleavage Enzyme 7%
• Steroids 7%
• Equine Gonadotropins 7%
• Androgen Antagonists 6%
• bisphenol A 6%
• Estrogen Receptor Modulators 6%
• Leydig Cells 5%
• Granulosa Cells 5%
• Pesticides 5%
• Fertility 4%
• Androgens 4%
• Estradiol 4%
• Atrophy 4%
• Rodentia 4%
• Estrogens 3%
• Messenger RNA 2%
• Liver 2%
• Animals 2%
• Serum 2%
• Proteins 1%

Chemical Compounds

• Methoxychlor 78%
• Progesterone 57%
• Cholesterol 43%
• Androgen 34%
• Metabolite 33%
• Cleavage 33%
• Estrogen 29%
• Antiandrogenic 21%
• Adrenodoxin 21%
• Steroid 12%
• Vinclozolin 11%
• Xenoestrogen 11%
• 4-Tert-Octylphenol 11%
• Antiandrogen 10%
• Estradiol 8%
• Pesticide 6%
• Biosynthesis 5%
• Block Like Crystal 4%
• Purity 3%
• Protein 2%