The microbial and host factors that govern Candida gastrointestinal colonization and dissemination

Animesh Anand Mishra, Andrew Y. Koh

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Candida species are among the most prevalent and abundant members of the gut mycobiota, with Candida albicans (CA) being the most prominent member. CA colonizes numerous mucosal surfaces, most notably the gastrointestinal (GI) and genitourinary tracts. In a healthy host, CA is a pathobiont that exists as a commensal but can become pathogenic if the host's immune system becomes suppressed. The microbial and/or host factors that dictate CA's ability to colonize mucosal surfaces and its ability to disseminate remain of great interest. Here, we review the recent advances and insights regarding Candida colonization and dissemination of the mammalian GI tract.

Original languageEnglish (US)
Pages (from-to)29-35
Number of pages7
JournalCurrent Opinion in Microbiology
Volume63
DOIs
StatePublished - Oct 2021

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases

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