The Minnesota Multiphasic Personality Inventory–2–Restructured Form (MMPI-2-RF) and Patient-Reported Outcomes Measurement Information System–29 (PROMIS-29) Comparison Study: Assessing for PROMIS-29 Depression and Anxiety Psychopathologic Cutoff Values Amongst Patients Undergoing Elective Complex Spine Procedures

Yves Jordan Kenfack, Paula Marie Mofor, Zachary Christian, Umaru Barrie, Luke Dosselman, Nickolas Stewart, Zachary D. Johnson, Jeffrey Dodds, Kristen Hall, Salah G. Aoun, Carlos A. Bagley

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The Minnesota Multiphasic Personality Inventory–2–Restructured Form (MMPI-2-RF) and the Patient-Reported Outcomes Measurement Information System–29 (PROMIS-29) are used to assess patient psychology, pain, and quality of life. As psychological factors, such as depression and anxiety, are associated with poor perioperative outcomes, we aim to translate MMPI-2-RF values to PROMIS-29 scores and establish cutoff values for PROMIS-29 anxiety and depression domains that might warrant attention preoperatively. Methods: Seventy adult patients scheduled for an elective spinal surgery between July 2018 and February 2020 who completed both the MMPI-2-RF and PROMIS-29 preoperatively at a single institution were reviewed. Results: Patients with MMPI-2-RF scores of 65 or greater (the cutoff for psychopathology) in the emotional/internalizing dysfunction scale (4.29%) had an average PROMIS-29 depression score of 14.33, which is significantly higher than the control group's (<65 score) 8.49 score (P = 0.04). Similarly, those demonstrating psychopathology on the demoralization (4.29%) and helplessness/hopelessness (4.29%) scales had average PROMIS-29 depression scores significantly higher than the control group's averages (15.33 vs. 8.45, P = 0.02 and 14.33 vs. 8.49, P = 0.04, respectively). Patients with an MMPI-2-RF score of 65 or greater on the emotional/internalizing dysfunction (4.29%), stress/worry (10.00%), and anxiety (7.14%) scales had average PROMIS-29 anxiety domain scores of 15, 15, and 15, respectively, which were significantly greater than that of the control group's scores (8.94, P = 0.04; 8.75, P = 0.004; and 8.55, P < 0.001, respectively). Conclusions: PROMIS-29 scores of 15 or greater on the depression and anxiety domains may have psychopathologies that warrant addressing, given their increased likelihood of having poor outcomes.

Original languageEnglish (US)
JournalWorld neurosurgery
DOIs
StateAccepted/In press - 2022

Keywords

  • Anxiety
  • Depression
  • MMPI-2-RF
  • Patient-reported
  • PROMIS-29
  • Psychology
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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