The myoadipose flap: A new composite

William P. Adams, John R. Griffin, Ronald M. Friedman, Rod J. Rohrich, Jack B. Robinson

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A prefabricated composite fat flap consisting of muscle woven into an anatomically distinct fat pad was studied in a rabbit model. In 17 rabbits, a 2-cm strip of latissimus dorsi was woven into the parascapular fat pad on one side, with the contralateral fat pad serving as a control. At 3 weeks, the endogenous blood supply of both the control and the experimental fat pads was isolated and ligated, and the composite fat/muscle flap was transferred to the chest wall. At 6 weeks, animals were killed, and flaps were analyzed for length, width, and weight; perfused with fluorescein or lead oxide; and examined histologically. Significant differences were found between the control and experimental fat pads with regard to weight and length. Experimental flaps were found to be perfused fully with fluorescein and lead oxide; control fat pads were found not to be perfused. The lead oxide group revealed extensive growth of blood vessels from the latissimus graft into the experimental fat pad. No vessels were visualized in the controls. Finally, sections of the control and experimental flaps were analyzed histologically. A preponderance of viable fat, with evidence of neovascularization, was found in experimental flaps, compared with the necrotic fat that characterized the controls. We conclude that prefabrication of a fat flap is possible and may have extensive application in various areas of plastic surgery.

Original languageEnglish (US)
Pages (from-to)735-740
Number of pages6
JournalPlastic and Reconstructive Surgery
Volume102
Issue number3
StatePublished - Sep 1998

Fingerprint

Adipose Tissue
Fats
Fluorescein
Rabbits
Weights and Measures
Muscles
Superficial Back Muscles
Thoracic Wall
Plastic Surgery
Blood Vessels
Transplants
Growth
lead oxide

ASJC Scopus subject areas

  • Surgery

Cite this

Adams, W. P., Griffin, J. R., Friedman, R. M., Rohrich, R. J., & Robinson, J. B. (1998). The myoadipose flap: A new composite. Plastic and Reconstructive Surgery, 102(3), 735-740.

The myoadipose flap : A new composite. / Adams, William P.; Griffin, John R.; Friedman, Ronald M.; Rohrich, Rod J.; Robinson, Jack B.

In: Plastic and Reconstructive Surgery, Vol. 102, No. 3, 09.1998, p. 735-740.

Research output: Contribution to journalArticle

Adams, WP, Griffin, JR, Friedman, RM, Rohrich, RJ & Robinson, JB 1998, 'The myoadipose flap: A new composite', Plastic and Reconstructive Surgery, vol. 102, no. 3, pp. 735-740.
Adams WP, Griffin JR, Friedman RM, Rohrich RJ, Robinson JB. The myoadipose flap: A new composite. Plastic and Reconstructive Surgery. 1998 Sep;102(3):735-740.
Adams, William P. ; Griffin, John R. ; Friedman, Ronald M. ; Rohrich, Rod J. ; Robinson, Jack B. / The myoadipose flap : A new composite. In: Plastic and Reconstructive Surgery. 1998 ; Vol. 102, No. 3. pp. 735-740.
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