TY - JOUR
T1 - The nature of the Ln3+ -angiotensin II complex. A 13C nmr study of the binding of Yb3+ to angiotensin ii
AU - Lenkinski, Robert E.
AU - Stephens, Richard L.
N1 - Funding Information:
Comprehensive Cancer Center of the University of Alabama in Birmingham operated under a grant from the U.S. Public Health Service, CA-13148 (to John R. Durant, M. D., and Jerry D. Glickson. Ph.D.). This work was supported by a grant from the U.S. Public Health Service, AM-21980 (to R.E.L.) and by a Postdoctoral Fellowship of the National Library of Medicine, U.S. Public Health Service grant LM-0701503 (to R.L.S.).
PY - 1983/4
Y1 - 1983/4
N2 - The nature of the Yb3+-angiotensin II complex is examined by 13C nuclear magnetic resonance. The ytterbium-induced shifts of most resonances are observed to be strongly dependent on pD, while a few are observed to be largely independent of pD. These observations are shown to be consistent with stepwise binding of the lanthanide ion to the carboxylates of aspartic acid and the C-terminus.
AB - The nature of the Yb3+-angiotensin II complex is examined by 13C nuclear magnetic resonance. The ytterbium-induced shifts of most resonances are observed to be strongly dependent on pD, while a few are observed to be largely independent of pD. These observations are shown to be consistent with stepwise binding of the lanthanide ion to the carboxylates of aspartic acid and the C-terminus.
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U2 - 10.1016/0162-0134(83)80021-X
DO - 10.1016/0162-0134(83)80021-X
M3 - Article
C2 - 6854317
AN - SCOPUS:0020741586
SN - 0162-0134
VL - 18
SP - 175
EP - 180
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 2
ER -