The neurology of decreased activity: Abulia

Shivani Ghoshal, Sankalp Gokhale, Gail Rebovich, Louis R. Caplan

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Delirium is sometimes defined as acute onset of either overactivity or underactivity. This article reviews the nature and clinico-anatomical locations of lesions in patients with reduced activity. The term abulia is used to describe global underactivity. Abulia is customarily explained by interruptions in frontal-subcortical circuitry. These interruptions can occur with lesions in the frontal lobes, caudate nuclei, midbrain, and thalamus. The article describes the anatomy of frontal and subcortical circuits and reviews in detail individual cases and series of patients with reduced initiative and activity who have had localized central nervous system lesions.

Original languageEnglish (US)
JournalReviews in Neurological Diseases
Volume8
Issue number3-4
DOIs
StatePublished - 2011

Fingerprint

Neurology
Delirium
Caudate Nucleus
Frontal Lobe
Mesencephalon
Thalamus
Anatomy
Central Nervous System

Keywords

  • Abulia
  • Akinesia
  • Apathy
  • Caudate nucleus
  • Delirium
  • Frontal lobe
  • Substantia nigra
  • Thalamus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

The neurology of decreased activity : Abulia. / Ghoshal, Shivani; Gokhale, Sankalp; Rebovich, Gail; Caplan, Louis R.

In: Reviews in Neurological Diseases, Vol. 8, No. 3-4, 2011.

Research output: Contribution to journalArticle

Ghoshal, Shivani ; Gokhale, Sankalp ; Rebovich, Gail ; Caplan, Louis R. / The neurology of decreased activity : Abulia. In: Reviews in Neurological Diseases. 2011 ; Vol. 8, No. 3-4.
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