The neuropsychiatric inventory: Comprehensive assessment of psychopathology in dementia

J. L. Cummings, M. Mega, K. Gray, S. Rosenberg-Thompson, D. A. Carusi, J. Gornbein

Research output: Contribution to journalArticle

5140 Scopus citations

Abstract

We developed a new instrument, the Neuropsychiatric Inventory (NPI), to assess 10 behavioral disturbances occurring in dementia patients: delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibition, irritability/lability, apathy, and aberrant motor activity. The NPI uses a screening strategy to minimize administration time, examining and scoring only those behavioral domains with positive responses to screening questions. Both the frequency and the severity of each behavior are determined. Information for the NPI is obtained from a caregiver familiar with the patient’s behavior. Studies reported here demonstrate the content and concurrent validity as well as between-rater, test-retest, and internal consistency reliability; the instrument is both valid and reliable. The NPI has the advantages of evaluating a wider range of psychopathology than existing instruments, soliciting information that may distinguish among different etiologies of dementia, differentiating between severity and frequency of behavioral changes, and minimizing administration time.

Original languageEnglish (US)
Pages (from-to)2308-2314
Number of pages7
JournalNeurology
Volume44
Issue number12
StatePublished - Dec 1994

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'The neuropsychiatric inventory: Comprehensive assessment of psychopathology in dementia'. Together they form a unique fingerprint.

  • Cite this

    Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., & Gornbein, J. (1994). The neuropsychiatric inventory: Comprehensive assessment of psychopathology in dementia. Neurology, 44(12), 2308-2314.