The opposed influences of β-adrenergic stimulation and adenosine on the frequency-force relationship of isolated left atria of guinea-pigs

D. Hilgemann; R. Englert; H. J. Mensing

doi:10.1007/BF01934040

The opposed influences of β-adrenergic stimulation and adenosine on the frequency-force relationship of isolated left atria of guinea-pigs

D. Hilgemann, R. Englert, H. J. Mensing

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The normal frequency-force relationship of left guinea-pig atria can be largely suspended when strong β-adrenergic stimulation by orciprenaline is antagonized by the negative inotropic effect of adenosine, so that contraction amplitude is nearly equal at an intermediate level over a wide range of stimulation rates. Curves obtained with a new method for recording continuous frequency-force loops are presented.

Original language	English (US)
Pages (from-to)	1629-1631
Number of pages	3
Journal	Experientia
Volume	33
Issue number	12
DOIs	https://doi.org/10.1007/BF01934040
State	Published - Dec 1977

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/BF01934040

Cite this

@article{9817bafe880e4fd7ad82f4f2d02ab349,

title = "The opposed influences of β-adrenergic stimulation and adenosine on the frequency-force relationship of isolated left atria of guinea-pigs",

abstract = "The normal frequency-force relationship of left guinea-pig atria can be largely suspended when strong β-adrenergic stimulation by orciprenaline is antagonized by the negative inotropic effect of adenosine, so that contraction amplitude is nearly equal at an intermediate level over a wide range of stimulation rates. Curves obtained with a new method for recording continuous frequency-force loops are presented.",

author = "D. Hilgemann and R. Englert and Mensing, {H. J.}",

year = "1977",

month = dec,

doi = "10.1007/BF01934040",

language = "English (US)",

volume = "33",

pages = "1629--1631",

journal = "Experientia",

issn = "0014-4754",

publisher = "Birkhauser Verlag Basel",

number = "12",

}

TY - JOUR

T1 - The opposed influences of β-adrenergic stimulation and adenosine on the frequency-force relationship of isolated left atria of guinea-pigs

AU - Hilgemann, D.

AU - Englert, R.

AU - Mensing, H. J.

PY - 1977/12

Y1 - 1977/12

N2 - The normal frequency-force relationship of left guinea-pig atria can be largely suspended when strong β-adrenergic stimulation by orciprenaline is antagonized by the negative inotropic effect of adenosine, so that contraction amplitude is nearly equal at an intermediate level over a wide range of stimulation rates. Curves obtained with a new method for recording continuous frequency-force loops are presented.

AB - The normal frequency-force relationship of left guinea-pig atria can be largely suspended when strong β-adrenergic stimulation by orciprenaline is antagonized by the negative inotropic effect of adenosine, so that contraction amplitude is nearly equal at an intermediate level over a wide range of stimulation rates. Curves obtained with a new method for recording continuous frequency-force loops are presented.

UR - http://www.scopus.com/inward/record.url?scp=0017724387&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017724387&partnerID=8YFLogxK

U2 - 10.1007/BF01934040

DO - 10.1007/BF01934040

M3 - Article

C2 - 590458

AN - SCOPUS:0017724387

SN - 0014-4754

VL - 33

SP - 1629

EP - 1631

JO - Experientia

JF - Experientia

IS - 12

ER -

The opposed influences of β-adrenergic stimulation and adenosine on the frequency-force relationship of isolated left atria of guinea-pigs

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this