The periportal collar: A CT sign of liver transplant rejection

R. J. Wechsler, S. J. Munoz, L. Needleman, A. B. Kurtz, C. L. Miller, S. L. Yang, W. C. Maddrey, B. E. Jarrelll

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

A low-attenuation region around the peripheral portal tracts (periportal collar) was noted on 13 of 43 computed tomographic studies obtained in 17 patients who had undergone 20 orthotopic liver transplantations. This region was then correlated with acute liver transplant rejection. The periportal collar as a sign of rejection has a sensitivity of 1.0, a specificity of 0.86, a negative predictive value of 1.0, and a positive predictive value of 0.62. This sign corresponds histopathologically with the lymphocytic portal infiltration that occurs during acute liver transplant rejection. Though viral hepatitis and nonspecific portal triad edema can also result in a periportal collar, acute liver rejection is strongly suggested when this sign is seen after liver transplantation. Early diagnosis and confirmation of rejection permit faster and more appropriate clinical intervention.

Original languageEnglish (US)
Pages (from-to)57-60
Number of pages4
JournalRadiology
Volume165
Issue number1
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'The periportal collar: A CT sign of liver transplant rejection'. Together they form a unique fingerprint.

  • Cite this

    Wechsler, R. J., Munoz, S. J., Needleman, L., Kurtz, A. B., Miller, C. L., Yang, S. L., Maddrey, W. C., & Jarrelll, B. E. (1987). The periportal collar: A CT sign of liver transplant rejection. Radiology, 165(1), 57-60. https://doi.org/10.1148/radiology.165.1.3306790