The PpaA/AerR regulators of photosynthesis gene expression from anoxygenic phototrophic proteobacteria contain heme-binding SCHIC domains

Oleg V. Moskvin, Marie Alda Gilles-Gonzalez, Mark Gomelsky

Research output: Contribution to journalArticle

15 Scopus citations


The SCHIC domain of the B12-binding domain family present in the Rhodobacter sphaeroides AppA protein binds heme and senses oxygen. Here we show that the predicted SCHIC domain PpaA/AerR regulators also bind heme and respond to oxygen in vitro, despite their low sequence identity with AppA.

Original languageEnglish (US)
Pages (from-to)5253-5256
Number of pages4
JournalJournal of bacteriology
Issue number19
StatePublished - Oct 1 2010


ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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