The prevalence of Barrett's esophagus in patients with chronic peptic esophageal strictures

Stuart Jon Spechler, Harry Sperber, Wilhelm G. Doos, Elihu M. Schimmel

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

Both Barrett's esophagus and peptic stricture of the esophagus are consequences of chronic reflux esophagitis. Barrett's esophagus appears to be a premalignant condition, and continued histologic surveillance for dysplasia and carcinoma has been recommended for affected patients. While patients with peptic esophageal strictures and persistent reflux are at risk for the development of Barrett's epithelium, such patients often do not receive continued histologic surveillance if Barrett's epithelium is not identified on the initial endoscopic evaluation. Using endoscopic and peroral aspiration biopsy techniques, we studied the prevalence of Barrett's esophagus in 25 patients with chronic peptic esophageal strictures in whom Barrett's epithelium had not been identified did not have Barrett's esophagus was found to have an undifferentiated esophageal carcinoma. We conclude that patients with chronic peptic esophageal strictures frequently have Barrett's esophagus. A program of continued histologic surveillance seems advisable for such patients.

Original languageEnglish (US)
Pages (from-to)769-774
Number of pages6
JournalDigestive Diseases and Sciences
Volume28
Issue number9
DOIs
StatePublished - Sep 1 1983

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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