The question of disproportionate impairments in visual and auditory information processing in multiple sclerosis

Bruce J. Diamond; John DeLuca; Heakyung Kim; Sharon M. Kelley

doi:10.1080/01688639708403834

The question of disproportionate impairments in visual and auditory information processing in multiple sclerosis

Bruce J. Diamond, John DeLuca, Heakyung Kim, Sharon M. Kelley

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Abstract

The present study was conducted to investigate the hypothesis that subjects with MS have a disproportionate impairment in the phonological loop of working memory and whether such impairment is domain-specific. This was assessed by comparing performance in subjects with MS across both the visual (using the Paced Visual Serial Addition Test: PVSAT) and auditory (using the Paced Auditory Serial Addition Test: PASAT) domains. In addition, we assessed the role of processing speed in mediating performance deficits. The results showed that: (1) Although all subjects performed better on the PVSAT versus the PASAT, no disproportionate modality-specific differences were observed in the MS group relative to controls; and (2) the rate of decline across trials in the MS and healthy control groups did not differ on either the PVSAT or PASAT. Implications of the results are discussed within the context of a working memory model.

Original language	English (US)
Pages (from-to)	34-42
Number of pages	9
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	19
Issue number	1
DOIs	https://doi.org/10.1080/01688639708403834
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology
Neuropsychology and Physiological Psychology
Neurology
Clinical Psychology

Access to Document

10.1080/01688639708403834

Cite this

@article{d9769018029b4055b15bb504b4b24d9f,

title = "The question of disproportionate impairments in visual and auditory information processing in multiple sclerosis",

abstract = "The present study was conducted to investigate the hypothesis that subjects with MS have a disproportionate impairment in the phonological loop of working memory and whether such impairment is domain-specific. This was assessed by comparing performance in subjects with MS across both the visual (using the Paced Visual Serial Addition Test: PVSAT) and auditory (using the Paced Auditory Serial Addition Test: PASAT) domains. In addition, we assessed the role of processing speed in mediating performance deficits. The results showed that: (1) Although all subjects performed better on the PVSAT versus the PASAT, no disproportionate modality-specific differences were observed in the MS group relative to controls; and (2) the rate of decline across trials in the MS and healthy control groups did not differ on either the PVSAT or PASAT. Implications of the results are discussed within the context of a working memory model.",

author = "Diamond, {Bruce J.} and John DeLuca and Heakyung Kim and Kelley, {Sharon M.}",

note = "Funding Information: * The work of Dr. Diamond was supported by Rehabilitation Services Administration Grant H1295 10006 and NIH Grant 5T32HD07417. This work was also supported in part by Grants 110 and 125 from the Henry H. Kessler Foundation, Inc. The authors wish to acknowledge Michelle McGrath, Cheryl Egan, Virve-Leena Vilpponen, Thomas S. Lee, and Stephanie A. Gross. A special thanks to Irene Furhmeister, Mary Ann Solimine, and Dr. John Towse, University of London, Royal Holloway College, England for his comments on an earlier version of this manuscript. This study was presented in part at the Annual Meeting of the American Psychological Association, August 13th, 1994, Los Angeles, CA. Address correspondence to: Drs. Bruce J. Diamond or John DeLuca, Kessler Institute for Rehabilitation, Neuro-psychologylNeuroscience Laboratory, Department of Research, 1199 Pleasant Valley Way, West Orange, NJ 07052. USA. Accepted for publication: December 20, 1995.",

year = "1997",

doi = "10.1080/01688639708403834",

language = "English (US)",

volume = "19",

pages = "34--42",

journal = "Journal of Clinical and Experimental Neuropsychology",

issn = "1380-3395",

publisher = "Psychology Press Ltd",

number = "1",

}

TY - JOUR

T1 - The question of disproportionate impairments in visual and auditory information processing in multiple sclerosis

AU - Diamond, Bruce J.

AU - DeLuca, John

AU - Kim, Heakyung

AU - Kelley, Sharon M.

N1 - Funding Information: * The work of Dr. Diamond was supported by Rehabilitation Services Administration Grant H1295 10006 and NIH Grant 5T32HD07417. This work was also supported in part by Grants 110 and 125 from the Henry H. Kessler Foundation, Inc. The authors wish to acknowledge Michelle McGrath, Cheryl Egan, Virve-Leena Vilpponen, Thomas S. Lee, and Stephanie A. Gross. A special thanks to Irene Furhmeister, Mary Ann Solimine, and Dr. John Towse, University of London, Royal Holloway College, England for his comments on an earlier version of this manuscript. This study was presented in part at the Annual Meeting of the American Psychological Association, August 13th, 1994, Los Angeles, CA. Address correspondence to: Drs. Bruce J. Diamond or John DeLuca, Kessler Institute for Rehabilitation, Neuro-psychologylNeuroscience Laboratory, Department of Research, 1199 Pleasant Valley Way, West Orange, NJ 07052. USA. Accepted for publication: December 20, 1995.

PY - 1997

Y1 - 1997

N2 - The present study was conducted to investigate the hypothesis that subjects with MS have a disproportionate impairment in the phonological loop of working memory and whether such impairment is domain-specific. This was assessed by comparing performance in subjects with MS across both the visual (using the Paced Visual Serial Addition Test: PVSAT) and auditory (using the Paced Auditory Serial Addition Test: PASAT) domains. In addition, we assessed the role of processing speed in mediating performance deficits. The results showed that: (1) Although all subjects performed better on the PVSAT versus the PASAT, no disproportionate modality-specific differences were observed in the MS group relative to controls; and (2) the rate of decline across trials in the MS and healthy control groups did not differ on either the PVSAT or PASAT. Implications of the results are discussed within the context of a working memory model.

AB - The present study was conducted to investigate the hypothesis that subjects with MS have a disproportionate impairment in the phonological loop of working memory and whether such impairment is domain-specific. This was assessed by comparing performance in subjects with MS across both the visual (using the Paced Visual Serial Addition Test: PVSAT) and auditory (using the Paced Auditory Serial Addition Test: PASAT) domains. In addition, we assessed the role of processing speed in mediating performance deficits. The results showed that: (1) Although all subjects performed better on the PVSAT versus the PASAT, no disproportionate modality-specific differences were observed in the MS group relative to controls; and (2) the rate of decline across trials in the MS and healthy control groups did not differ on either the PVSAT or PASAT. Implications of the results are discussed within the context of a working memory model.

UR - http://www.scopus.com/inward/record.url?scp=0030893872&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030893872&partnerID=8YFLogxK

U2 - 10.1080/01688639708403834

DO - 10.1080/01688639708403834

M3 - Article

C2 - 9071639

AN - SCOPUS:0030893872

SN - 1380-3395

VL - 19

SP - 34

EP - 42

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

IS - 1

ER -

The question of disproportionate impairments in visual and auditory information processing in multiple sclerosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this