TY - JOUR
T1 - The relationship between asthma and depression in a community-based sample
AU - Akula, Mahima
AU - Kulikova, Alexandra
AU - Khan, David A.
AU - Brown, E. Sherwood
N1 - Funding Information:
Dr. Brown had a research grant from NIH, The Stanley Medical Research Institute, and Otsuka. Dr. Khan reports research funding from NIH, a speaker honorarium from Genentech, and service on a data and safety monitoring committee for Aim-mune. Ms. Akula and Ms. Kulikova have nothing to declare. Research reported in this publication was supported, in part, by the Science Teacher Access to Resources at Southwestern (STARS) program and the National Center for Advancing Translational Sciences of the National Institutes of Health under award Number UL1TR001105. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
Publisher Copyright:
© 2017, © 2017 Taylor & Francis Group, LLC.
PY - 2018/12/2
Y1 - 2018/12/2
N2 - Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.
AB - Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.
KW - Management/control
KW - morbidity and mortality
KW - quality of life
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U2 - 10.1080/02770903.2017.1418885
DO - 10.1080/02770903.2017.1418885
M3 - Article
C2 - 29336633
AN - SCOPUS:85061822314
SN - 0277-0903
VL - 55
SP - 1271
EP - 1277
JO - Journal of Asthma
JF - Journal of Asthma
IS - 12
ER -