The relationship between asthma and depression in a community-based sample

Mahima Akula, Alexandra Kulikova, David A Khan, Edson S Brown

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.

Original languageEnglish (US)
Pages (from-to)1271-1277
Number of pages7
JournalJournal of Asthma
Volume55
Issue number12
DOIs
StatePublished - Dec 2 2018

Fingerprint

Asthma
Depression
Psychiatry
Equipment and Supplies
Mental Disorders
Population
Mental Health
Body Mass Index
Logistic Models
Smoking
History
Demography
Research

Keywords

  • Management/control
  • morbidity and mortality
  • quality of life

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

The relationship between asthma and depression in a community-based sample. / Akula, Mahima; Kulikova, Alexandra; Khan, David A; Brown, Edson S.

In: Journal of Asthma, Vol. 55, No. 12, 02.12.2018, p. 1271-1277.

Research output: Contribution to journalArticle

Akula, Mahima ; Kulikova, Alexandra ; Khan, David A ; Brown, Edson S. / The relationship between asthma and depression in a community-based sample. In: Journal of Asthma. 2018 ; Vol. 55, No. 12. pp. 1271-1277.
@article{90310dae7630405497d3079b490cd0f6,
title = "The relationship between asthma and depression in a community-based sample",
abstract = "Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4{\%} of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95{\%} CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95{\%}CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.",
keywords = "Management/control, morbidity and mortality, quality of life",
author = "Mahima Akula and Alexandra Kulikova and Khan, {David A} and Brown, {Edson S}",
year = "2018",
month = "12",
day = "2",
doi = "10.1080/02770903.2017.1418885",
language = "English (US)",
volume = "55",
pages = "1271--1277",
journal = "Journal of Asthma",
issn = "0277-0903",
publisher = "Informa Healthcare",
number = "12",

}

TY - JOUR

T1 - The relationship between asthma and depression in a community-based sample

AU - Akula, Mahima

AU - Kulikova, Alexandra

AU - Khan, David A

AU - Brown, Edson S

PY - 2018/12/2

Y1 - 2018/12/2

N2 - Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.

AB - Objective: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. Methods: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. Results: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280–2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106–2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. Conclusions: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.

KW - Management/control

KW - morbidity and mortality

KW - quality of life

UR - http://www.scopus.com/inward/record.url?scp=85061822314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061822314&partnerID=8YFLogxK

U2 - 10.1080/02770903.2017.1418885

DO - 10.1080/02770903.2017.1418885

M3 - Article

C2 - 29336633

AN - SCOPUS:85061822314

VL - 55

SP - 1271

EP - 1277

JO - Journal of Asthma

JF - Journal of Asthma

SN - 0277-0903

IS - 12

ER -