The relevance of somatosensory auras in refractory temporal lobe epilepsies

Ghazala Perven, Ruta Yardi, Juan Bulacio, Imad Najm, William Bingaman, Jorge Gonzalez-Martinez, Lara Jehi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study is to look at the prevalence, characteristics, and prognostic value of somatosensory auras (SSAs) in patients who have undergone temporal lobe epilepsy (TLE) surgery to treat drug-resistant focal epilepsy. We retrospectively reviewed all patients with drug-resistant epilepsy who underwent TLE surgery at Cleveland Clinic between 2005 and 2010 (n = 333) to study the prevalence, characteristics, and prognostic implications of SSA in the context of TLE surgery. Analyses were performed using two seizure outcome definitions: complete seizure freedom and Engel classification. Of the 333 patients, 26 (7.8%) had SSA. Almost half (12 patients) had unilateral sensory symptoms, whereas the rest had bilateral symptoms. Tingling and numbness were the most frequently reported sensations. Compared to their non-SSA counterparts, patients with SSA had the same clinical and imaging characteristics, but had a higher rate of breakthrough seizures (p = 0.03), although most (54%) were still able to achieve Engel class of I (p = 0.02). Based on our results we would encourage detailed presurgical testing, which may include an invasive evaluation to analyze the extent of the epileptogenic zone in patients with SSA and suspected TLE.

Original languageEnglish (US)
Pages (from-to)e143-e148
JournalEpilepsia
Volume56
Issue number10
DOIs
StatePublished - Oct 1 2015

Fingerprint

Temporal Lobe Epilepsy
Epilepsy
Seizures
Partial Epilepsy
Hypesthesia
Cross-Sectional Studies

Keywords

  • Refractory temporal lobe epilepsy
  • Somatosensory aura
  • Surgical outcome

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Perven, G., Yardi, R., Bulacio, J., Najm, I., Bingaman, W., Gonzalez-Martinez, J., & Jehi, L. (2015). The relevance of somatosensory auras in refractory temporal lobe epilepsies. Epilepsia, 56(10), e143-e148. https://doi.org/10.1111/epi.13110

The relevance of somatosensory auras in refractory temporal lobe epilepsies. / Perven, Ghazala; Yardi, Ruta; Bulacio, Juan; Najm, Imad; Bingaman, William; Gonzalez-Martinez, Jorge; Jehi, Lara.

In: Epilepsia, Vol. 56, No. 10, 01.10.2015, p. e143-e148.

Research output: Contribution to journalArticle

Perven, G, Yardi, R, Bulacio, J, Najm, I, Bingaman, W, Gonzalez-Martinez, J & Jehi, L 2015, 'The relevance of somatosensory auras in refractory temporal lobe epilepsies', Epilepsia, vol. 56, no. 10, pp. e143-e148. https://doi.org/10.1111/epi.13110
Perven G, Yardi R, Bulacio J, Najm I, Bingaman W, Gonzalez-Martinez J et al. The relevance of somatosensory auras in refractory temporal lobe epilepsies. Epilepsia. 2015 Oct 1;56(10):e143-e148. https://doi.org/10.1111/epi.13110
Perven, Ghazala ; Yardi, Ruta ; Bulacio, Juan ; Najm, Imad ; Bingaman, William ; Gonzalez-Martinez, Jorge ; Jehi, Lara. / The relevance of somatosensory auras in refractory temporal lobe epilepsies. In: Epilepsia. 2015 ; Vol. 56, No. 10. pp. e143-e148.
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