TY - JOUR
T1 - The role of bacterial biofilms in device-associated infection
AU - Deva, Anand K.
AU - Adams, William P.
AU - Vickery, Karen
PY - 2013/11
Y1 - 2013/11
N2 - There is increasing evidence that bacterial biofilm is responsible for the failure of medical devices, leading to device-associated infection. As plastic surgeons, we are among the leading users of prostheses in surgery, and it is important that we are kept informed of this growing problem. This article summarizes the pathogenesis of device-associated infection, outlines the evidence for such infection in a number of medical devices, and outlines operative strategies aimed at reducing the risk of bacterial contamination at the time of device deployment. It also outlines strategies under investigation to combat the development of device-associated infection.
AB - There is increasing evidence that bacterial biofilm is responsible for the failure of medical devices, leading to device-associated infection. As plastic surgeons, we are among the leading users of prostheses in surgery, and it is important that we are kept informed of this growing problem. This article summarizes the pathogenesis of device-associated infection, outlines the evidence for such infection in a number of medical devices, and outlines operative strategies aimed at reducing the risk of bacterial contamination at the time of device deployment. It also outlines strategies under investigation to combat the development of device-associated infection.
UR - http://www.scopus.com/inward/record.url?scp=84887321256&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887321256&partnerID=8YFLogxK
U2 - 10.1097/PRS.0b013e3182a3c105
DO - 10.1097/PRS.0b013e3182a3c105
M3 - Article
C2 - 23924649
AN - SCOPUS:84887321256
SN - 0032-1052
VL - 132
SP - 1319
EP - 1328
JO - Plastic and reconstructive surgery
JF - Plastic and reconstructive surgery
IS - 5
ER -