Abstract
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pain syndrome identified by the presence of noninfectious pelvic or perineal pain lasting longer than 3 months. Current diagnoses and treatments for the syndrome solely depend on and target symptoms, respectively. Thus far, the mechanistic disturbances responsible for the pathogenesis of CP/CPPS have remained largely elusive and treatments, and therefore, continue to be ineffective. To move toward successful management and treatment of CP/CPPS, it is necessary to elicit the underlying biological mechanisms responsible for the syndrome. Therefore, a phenotyping system that is able to bridge the gap between current symptom-based diagnosis and future mechanistic approaches to diagnosis and treatment is needed. In this article, we examine current CP/CPPS phenotyping systems, analyze their utility, and make suggestions for changes in clinical approaches to the syndrome that would both promulgate a mechanistic understanding and advance treatment approaches.
Original language | English (US) |
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Pages (from-to) | 297-303 |
Number of pages | 7 |
Journal | Current urology reports |
Volume | 12 |
Issue number | 4 |
DOIs | |
State | Published - Aug 2011 |
Externally published | Yes |
Keywords
- CP/CPPS
- Chronic prostatitis/chronic pelvic pain syndrome
- DABBEC
- Phenotype
- Phenotyping
- UPOINT
ASJC Scopus subject areas
- Urology