The role of the vascular endothelium in inflammatory syndromes, atherogenesis, and the propagation of disease

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28 Citations (Scopus)

Abstract

The vascular endothelium is intimately involved in a wide variety of normal physiological processes, including coagulation/anticoagulation, the maintenance of vascular tone, and pathological processes, including reperfusion injury, inflammatory syndromes, and tumor cell metastasis. This review discusses the importance of increased adhesive molecule expression on the endothelial surface in promoting circulating inflammatory cell- endothelial adherence in inflammatory conditions, as well as the role of the vascular endothelium in reperfusion injury, altered microvascular permeability states, and atherogenesis.

Original languageEnglish (US)
Pages (from-to)316-321
Number of pages6
JournalJournal of Cardiothoracic and Vascular Anesthesia
Volume11
Issue number3
DOIs
StatePublished - May 1997

Fingerprint

Vascular Endothelium
Reperfusion Injury
Atherosclerosis
Physiological Phenomena
Capillary Permeability
Pathologic Processes
Adhesives
Blood Vessels
Endothelial Cells
Maintenance
Neoplasm Metastasis
Neoplasms

Keywords

  • adhesion molecules
  • atherogenesis
  • inflammation
  • nitric oxide
  • vascular endothelium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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