The role of the vascular endothelium in inflammatory syndromes, atherogenesis, and the propagation of disease

Research output: Contribution to journalReview article

28 Scopus citations


The vascular endothelium is intimately involved in a wide variety of normal physiological processes, including coagulation/anticoagulation, the maintenance of vascular tone, and pathological processes, including reperfusion injury, inflammatory syndromes, and tumor cell metastasis. This review discusses the importance of increased adhesive molecule expression on the endothelial surface in promoting circulating inflammatory cell- endothelial adherence in inflammatory conditions, as well as the role of the vascular endothelium in reperfusion injury, altered microvascular permeability states, and atherogenesis.

Original languageEnglish (US)
Pages (from-to)316-321
Number of pages6
JournalJournal of cardiothoracic and vascular anesthesia
Issue number3
StatePublished - May 1997



  • adhesion molecules
  • atherogenesis
  • inflammation
  • nitric oxide
  • vascular endothelium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

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